Tuesday June 23^rd 2026

 

Executive Committee Meeting (Invite only)

15:00 - 16:30 Tuesday, 23rd June, 2026

Location: Harvard

 

Welcome Reception

17:00 - 19:30 Tuesday, 23rd June, 202

Location: E2 + Foyer

Wednesday June 24^th 2026

Welcome Remarks

09:00 - 09:15 Wednesday, 24th June, 2026
Location: Uva Full

 

Plenary: Wouter Peyrot

09:15 - 10:15 Wednesday, 24th June, 2026
Location: Uva Full

 

Coffee Break

10:15 - 10:45 Wednesday, 24th June, 2026
Location: E2 + Foyer

 
Full Symposium 1
The Genetic Landscape of Anxiety: Symptoms, Disorders, Comorbidities, and Temporal Trends

10:45 - 12:00 Wednesday, 24th June, 2026
Location: Uva 1-2 
Chair: Megan Skelton
Discussant: Helga Ask

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Genome-wide analyses of quantitative generalised anxiety symptom severity

Megan Skelton¹, Brittany Mitchell^2,3,4, Elham Assary¹, Danyang Li¹, Genevieve Morneau-Vaillancourt⁵, Alan Murphy⁶, Abigail ter Kuile⁷, Rujia Wang¹, Catharina Hartman⁸, Nick Martin², John Hettema⁹, Gerome Breen¹, Jonathan Coleman¹, Thalia Eley¹

¹King's College London, London, United Kingdom. ²QIMR Berghofer Medical Research Institute, Brisbane, Australia. ³The University of Queensland, Brisbane, Australia. ⁴Queensland University of Technology, Brisbane, Australia. ⁵University of Montreal, Montreal, Canada. ⁶Imperial College London, London, United Kingdom. ⁷University College London, London, United Kingdom. ⁸University of Groningen, Groningen, Netherlands. ⁹Texas A&M University, Bryan, USA

 

Bidirectional Associations and Genetic Background of Anxiety Disorders and General Medical Conditions

Anniina Tervi^1,2, Eos Suomalainen^1,2, Heidi Perälampi^1,2, Nelli Frilander^1,2, Joonas Naamanka^3,1,2, Sanni Ruuskanen^1,2, Jussi Hölttä^1,2, F FinnGen⁴, Anxiety Disorders Working Group Psychiatric Genomics Consortium⁵, Tiina Paunio^1,6,7, Jaana Suvisaari⁸, Marko Elovainio^2,8, Iiris Hovatta^1,2

¹SleepWell Research Program, University of Helsinki, Helsinki, Finland. ²Department of Psychology, Faculty of Medicine, University of Helsinki, Helsinki, Finland. ³Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Mannheim, Germany. ⁴Institute for Molecular Medicine Finland, HiLife, University of Helsinki, Helsinki, Finland. ⁵Texas A&M University College Medicine, Bryan, Texas, USA. ⁶Department of Psychiatry, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. ⁷Department of Public Health, Finnish Institute for Health and Welfare, Helsinki, Finland. ⁸Department of Healthcare and Social Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland

Temporal trends in anxiety symptoms and diagnoses among young people and associations with anxiety PGS

Johanne H. Pettersen^1,2, Ludvig D. Bjørndal^2,3, Laurie J. Hannigan^2,4,5, Robyn Wootton^2,6,7, Ragnhild E. Brandlistuen^2,3,8, Alexandra Havdahl^2,3,4, Ole A. Andreassen^1,9, Helga Ask^2,8

¹Centre for Precision Psychiatry, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. ²PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ³PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. ⁴Psychiatric Genetic Epidemiology Group, Research Department, Lovisenberg Diaconal Hospital, Oslo, Norway. ⁵Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ⁶The School of Psychology and Neuroscience, University of Bristol, Bristol, United Kingdom. ⁷MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ⁸Department of Child Health and Development, Norwegian Institute of Public Health, Oslo, Norway. ⁹Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

Genome-wide meta-analysis identifies genetic risk factors and implicates multiple body systems in panic attacks and disorder

Brittany Mitchell¹, Megan Skelton², Rujia Wang², Abigail ter Kuile³, Alan Murphy⁴, Genevieve Morneau-Vaillancourt⁵, Danyang Li², Elham Assary², Jihua Hu¹, Panic GWAS Group², Jonathan Coleman^2,6, Thalia Eley^2,6, Gerome Breen^2,6

¹QIMR Berghofer Medical Research Institute, Brisbane, Australia. ²Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom. ³Department of Clinical, Educational, and Health Psychology, University College London, London, United Kingdom. ⁴Department of Brain Sciences, Imperial College London, London, United Kingdom. ⁵Research Centre of the Montreal University Institute of Mental Health, University of Montreal, Montreal, Canada. ⁶National Institute for Health and Care Research Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom

 

Full Symposium 2

Advances in Trait-Based Genetic Analyses of Late-Onset Alzheimer's Disease (LOAD) and Related Dementia

10:45 - 12:00 Wednesday, 24th June, 2026
Location: Uva 3-4 
Chair: Alexander Sheppard
Discussant: Chandra Reynolds

Evaluating causal inference in the associations between hand grip strength and dementia risk in twins from the IGEMS consortium

Tara Lynn Henechowicz¹, Daniel E Gustavson¹, Luis Fernando Silva Castro De Araujo^2,3, Elina Sillanpää^4,5, Päivi Herranen^4,6, Jenae M. Neiderhiser⁷, Deborah Finkel^8,9, Chandra A Reynolds¹

¹Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, USA. ²Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA. ³Dept of Psychiatry, The University of Melbourne, Austin Health, Victoria, Australia. ⁴Gerontology Research Center and Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland. ⁵Wellbeing Services County of Central Finland, Central Finland, Finland. ⁶Folkhälsan Research Center, Helsinki, Finland. ⁷Department of Psychology, Penn State University, University Park, USA. ⁸Institute of Gerontology, School of Health and Welfare, Jönköping University, Jönköping, Sweden. ⁹Center for Economic and Social Research, University of Southern California, Los Angeles, USA

Longitudinal change in body mass index from mid- to late-life in relation to incident dementia

Yuling Yu¹, Chandra Reynolds², Ida Karlsson¹

¹Karolinska Institutet, Stockholm, Sweden. ²University of Colorado Boulder, Colorado, USA

**Public Science Presentation

Categorizing unique and shared genetic pathways of Late-Onset Alzheimer’s Dementia and Amyotrophic Lateral Sclerosis

Alexander Sheppard^1,2, Sophie Breunig^1,2, Jeremy Lawrence^1,2, Luke Schaffer^1,2, Andrew Grotzinger^1,2

¹University of Colorado Boulder, Boulder, USA. ²Institute for Behavioral Genetics, Boulder, USA

**Early Career Presentation

Revisiting modifiable risk factors forAlzheimer’s disease: evidence from Mendelian Randomization

Leona Knüsel^1,2, Isabelle Foote^3,4,5, Nicolas Goss^6,1,2, Jacques Fellay^7,8, Zoltán Kutalik^1,2,9

¹University of Lausanne, Department of Computational Biology, Lausanne, Switzerland. ²Swiss Institute for Bioinformatics, Lausanne, Switzerland. ³Queen Mary University of London, Wolfson Institute of Population Health, Centre for Preventive Neurology, London, United Kingdom. ⁴Barts Health NHS Trust, Academic Centre for Healthy Ageing, London, United Kingdom. ⁵University of Colorado Boulder, Institute for Behavioral Genetics, Colorado Boulder, USA. ⁶University of Lausanne, Metabolomics and Lipidomics Plattform, Lausanne, Switzerland. ⁷Ecole Polytechnique Federale de Lausanne, School of Life Sciences, Lausanne, Switzerland. ⁸Lausanne University Hospital and University of Lausanne, Precision Medicine Unit, Lausanne, Switzerland. ⁹University Center for Primary Care and Public Health, Lausanne, Switzerland

**Early Career Presentation

Full Symposium 3
Intergenerational Transmission of Education and ADHD - The Role of Parents Throughout Development

10:45 - 12:00 Wednesday, 24th June, 2026
Location: Erasmus 1 
Chair: Josefina Bernardo
Discussant: Elsje Van Bergen

How is parental educational attainment related to children’s school grades? – A Children-of-Twins Study of Grade Point Averages, teacher evaluations, and national exams

Josefina B Bernardo¹, Hans Fredrik Sunde², Fartein A Torvik^2,3, Elsje Van Bergen¹

¹Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. ³PROMENTA Research Centre, Department of Psychology, University of Oslo, Oslo, Norway

**Early Career Presentation

Sex, parental educational attainment, and birth month relate to ADHD diagnosis beyond symptoms and genetic liability

Britt Min¹, Elsje van Bergen², Mathias Valstad¹, Alexandra Havdahl³, Eivind Ystrom¹, Monica Melby-Lervag¹, Fartein Ask Torvik³

¹University of Oslo, Oslo, Norway. ²Vrije Universiteit, Amsterdam, Netherlands. ³Norwegian Institute of Public Health, Oslo, Norway

Charting the developmental interplay between ADHD and parental discipline from age 7 through 21 years

Sophie von Stumm

University of York, York, United Kingdom

**Early Career Presentation

The role of household chaos in the intergenerational transmission of ADHD

Alexandra Starr, Conor V. Dolan, Josefina B. Bernardo, Bruno Sauce, Elsje van Bergen

Department of Biological Psychology, VU Amsterdam, Amsterdam, Netherlands

 

Full Symposium 4
Untangling the Web: Advanced Genomic Strategies for Mapping Unique and Shared Genetic Architectures

10:45 - 12:00 Wednesday, 24th June, 2026
Location: Erasmus 2 
Chairs: Sophie Breunig & Jeremy Lawrence
Discussant: Michel Nivard

Prioritizing Modifiable Risk Factors for Psychiatric Disorders via Genomic Structural Equation Modeling

Sophie Breunig^1,2, Jeremy Lawrence^1,2, Lukas Schaffer^1,2, Alexander Sheppard^1,2, Andrew Grotzinger^1,2

¹Institute for Behavioral Genetics, Boulder, USA. ²University of Colorado, Boulder, Boulder, USA

**Early Career Presentation

Disentangling Direct and Mediated Genetic Effects on BMI Using Local Mediation Analysis

Jana S. Hirzinger¹, Christiaan A. de Leeuw¹, Danielle Posthuma^1,2, Rachel M. Brouwer¹

¹Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Department of Child and Adolescent Psychiatry and Psychology, Vrije Universiteit Medical Center, Amsterdam University Medical Center, Amsterdam, Netherlands

**Early Career Presentation

Disentangling the Genetic Heterogeneity of Major Depressive Disorder using GDIS

Anaïs Thijssen¹, Yuri Milaneschi¹, Meike Bartels², Brenda Penninx¹, Joëlle Pasman^1,3, Karin Verweij¹, Wouter Peyrot¹

¹Amsterdam UMC, Amsterdam, Netherlands. ²Vrije Universiteit, Amsterdam, Netherlands. ³Karolinska Institute, Stockholm, Sweden

**Early Career Presentation

Anthropometrically Independent Genetic Architecture of Cardiac Size and Function: Evidence from GWAS-by-Subtraction via Genomic SEM

Jeremy Lawrence¹, Sarah Abramowitz², Mike Levin², Scott Damrauer², Andrew Grotzinger¹

¹CU Boulder, Boulder, USA. ²University of Pennsylvania, Philadelphia, USA

**Early Career Presentation

Lunch & Mentoring Roundtables

12:00 - 13:00 Wednesday, 24th June, 2026
Location: EAST & Upper EAST

Full Symposium 5
Genetics of Depression Across the Lifecourse: From Adolescence and Young Adulthood to the Perinatal Period

13:00 - 14:15 Wednesday, 24th June, 2026
Location: Uva 1-2 
Chair: Lu Yi
Discussant: Alexander Neumann

Genome-wide association study of adolescent-onset depression

Poppy Grimes, Alex Kwong

University of Edinburgh, Edinburgh, United Kingdom

**Community, Accessibility, & Growth Presentation

Genetic divergence in early- and late-onset depression: implications for suicide risk and precision psychiatry

John Shorter¹, Joëlle Pasman², Siim Kurvits³, Andreas Jangmo⁴, Joonas Naamanka⁵, Martin Tesli⁶, Kelli Lehto³, Alfonso Buil⁷, Yi Lu⁸

¹Department of Science and Environment, Roskilde University, Roskilde, Denmark. ²Department of Psychiatry, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands. ³Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. ⁴Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway. ⁵SleepWell Research Program and Department of Psychology, Faculty of Medicine, University of Helsinki, Helsinki, Finland. ⁶Institute of Clinical Medicine, University of Oslo, Oslo, Norway. ⁷Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Copenhagen, Copenhagen University Hospital, Roskilde, Denmark. ⁸Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Genetic Architecture of Perinatal Depression: Disentangling perinatal-specific and general depression pathways

Mina Shahisavandi^1,2, Adriana P.C. Hermans^1,2, Charlotte Cecil^1,2, Manon H J Hillegers^1,2, Alexander Neumann^1,2

¹Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands. ²The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands

From Genetic Liability to Multilevel Stratification in Perinatal Psychiatry: Toward a Personalized Medicine

Benedetta Vai

IRCCS Ospedale San Raffael, Milano, Italy

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

Full Symposium 6

Genes and Time: A Dive Into the Temporal Dynamics of Human Phenotypes

13:00 - 14:15 Friday, 26th June, 2026
Location: Uva 1-2 
Chair: Luca Sclisizzo
Discussant: Michael C. Neale

Dissecting the spectrum of psychosis: leveraging time and dimensionality to explore multiple, functionally separable sources of genetic risk.

Luca Sclisizzo^1,2, David AA Baranger³, Margaret L Clapp Sullivan², Alexander S Hatoum², Carrie Burnett², Marco Del Giudice¹, Emma C Johnson²

¹Department of Life Sciences, University of Trieste, Trieste, Italy. ²Washington University School of Medicine, Saint Louis, Missouri, USA. ³Medical College of Wisconsin, Milwaukee, Wisconsin, USA

Genetic and environmental influences on developmental stability and rates of change in internalizing and externalizing symptoms across adolescence

Lydia Rader¹, Analicia Howard^1,2, Daniel Gustavson^2,1, Luis Araujo³, Michael Neale³, Pamela Madden⁴, Sylia Wilson⁵, Monica Luciana⁵, Hermine Maes³, Naomi Friedman^1,2

¹Institute for Behavioral Genetics, Boulder, USA. ²University of Colorado Boulder, Boulder, USA. ³Virginia Commonwealth University, Richmond, USA. ⁴Washington University in St Louis, St Louis, USA. ⁵University of Minnesota, Minneapolis, USA

Polygenic Influences on Developmental Timing and Hospitalization Patterning in Psychosis

Evan Giangrande^1,2, Anders Kämpe^3,4, Caitlin Ravichandran⁵, Jaana Suvisaari⁶, Markku Lähteenvuo⁷, Emilia Vartiainen³, SUPER-Finland Researchers³, Olli Pietiläinen^8,1, Aarno Palotie^3,1, Bruce Cohen⁹, Benjamin Neale^1,10, Jordan Smoller^11,1

¹Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. ²Analytic and Translational Genetics Unit and Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. ³Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. ⁴Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. ⁵Program for Neuropsychiatric Research, McLean HospitalMcLean Hospital, Belmont, MA, USA. ⁶Finnish Institute for Health and Welfare, Department of Healthcare and Social Welfare, Helsinki, Finland. ⁷Department of Forensic Psychiatry, University of Eastern Finland School of Medicine, Niuvanniemi Hospital, Kuopio, Finland. ⁸Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland. ⁹Program for Neuropsychiatric Research, McLean Hospital, Belmont, MA, USA. ¹⁰Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. ¹¹Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA

Understanding age-varying genetic effects: Methodological considerations and evidence from longitudinal genome-wide analyses

Tabea Schoeler

University of Lausanne, Lausanne, Switzerland

 
Full Symposium 7
Genetic Approaches to Music Engagement: Insights from GWAS and Twin Studies

13:00 - 14:15 Wednesday, 24th June, 2026
Location: Erasmus 1
Chair: Reyna Gordon
Discussant: Miriam Mosing

Unveiling shared genetic architecture between singing-related traits and human health.

Tanguy Rubat du Mérac^1,2, Penghao Xia^3,4, Jamee M. Berg², Peyton Coleman^1,5, Ole Birger V. Pedersen^6,7, Thomas F. Hansen^8,9, DBDS Consortium¹⁰, Kári Stefánsson¹¹, Miriam A. Mosing^3,4, Simon E. Fisher^12,13, Else Eising¹², Rósa S. Gísladóttir¹⁴, Reyna L. Gordon^2,15

¹Human Genetics Program, Vanderbilt University, Nashville, USA. ²Department of Otolaryngology - Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, USA. ³Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany. ⁴Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. ⁵Center for Digital Genomic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, USA. ⁶Dept. of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. ⁷Dept. of Clinical Immunology, Zealand University Hospital, Køge, Denmark. ⁸Translational Research Centre, Copenhagen University Hospital, Copenhagen, Denmark. ⁹DTU Health Tech, Technical University Hospital, Copenhagen, Denmark. ¹⁰Copenhagen University Hospital, Copenhagen, Denmark. ¹¹Faculty of Medicine, University of Iceland, Reykjavik, Iceland. ¹²Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ¹³Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands. ¹⁴Department of Icelandic and Comparative Cultural Studies, University of Iceland, Reykjavik, Iceland. ¹⁵epartment of Hearing & Speech Sciences, Vanderbilt University Medical Center, Nashville, USA

**Early Career Presentation

Heritability of Activity Engagement in Adolescents and Associations with Reading and Executive Functions

Mohini Karhadkar^1,2, Hermine Maes^3,4,5, Naomi Friedman^1,2, Miriam Lense^6,7,8, Chandra Reynolds^1,2, Reyna Gordon^6,9,10,11, Daniel Gustavson^1,2

¹Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, USA. ²Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, USA. ³Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA. ⁴Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA. ⁵Massey Cancer Center, Virginia Commonwealth University, Richmond, USA. ⁶Department of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, USA. ⁷Psychology and Human Development, Vanderbilt University, Nashville, USA. ⁸Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, USA. ⁹Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, USA. ¹⁰Vanderbilt Brain institute, Vanderbilt University, Nashville, USA. ¹¹Department of Hearing & Speed Sciences, Vanderbilt University Medical Center, Nashville, USA

**Early Career Presentation

The genetic architecture of musical achievement and training: a large-scale GWAS meta-analysis in ~100,000 individuals

Laura Wesseldijk¹, Penghao Xia¹, Tanguy du Mérac², Musicality Genomics Consortium Meta Analysis Working Group³, Fredrik Ullén¹, Simon Fisher⁴, Rosa Gisladottir⁵, Else Eising⁴, Reyna Gordon², Miriam Mosing¹

¹Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany. ²Van der Bilt, Nashville, USA. ³na, na, USA. ⁴Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ⁵Decode, Reykjavik, Iceland

Genome-wide study of five musicality traits demonstrates phenotypic and genetic links to language, intelligence, personality, and psychiatric disorders

Rósa Signý Gísladóttir¹, Agnar Helgason², Ole Birger Vesterager Pedersen^3,4, Thomas Folkmann Hansen^5,6, DBDS Consortium⁴, Kári Stefánsson⁷

¹Department of Icelandic and Comparative Cultural Studies, University of Iceland, Reykjavik, Iceland. ²Department of Anthropology, University of Iceland, Reykjavik, Iceland. ³Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark. ⁴Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. ⁵Translational Research Centre, Copenhagen University Hospital, Copenhagen, Denmark. ⁶DTU Health Tech, Technical University Hospital, Copenhagen, Denmark. ⁷Faculty of Medicine, University of Iceland, Reykjavik, Iceland

Full Symposium 8
Genetic Explanations: Beliefs, Boundaries, and Interpretation Across Domains

13:00 - 14:15 Wednesday, 24th June, 2026
Location: Erasmus 2
Chair: Matthew Lebowitz
Discussant: José Morosoli

Polygenic Score Researcher Perspectives on the Blurred Boundaries Between Social and Medical Traits

Margaret Waltz¹, Karen M. Meagher², Courtney Canter¹, Matthew Kucmanic³, Kristine J. Kuczynski¹, Anya E. R. Prince³, R. Jean Cadigan¹

¹University of North Carolina at Chapel Hill, Chapel Hill, USA. ²Temple University, Philadelphia, USA. ³University of Iowa, Iowa City, USA

**Early Career Presentation

**Public Science Presentation

U.S. Physicians' Genetic Knowledge and Genetic Attributions for Racial Disparities in Obesity

Matthew Lebowitz¹, Rebecca Pearl², Carolyn Tucker²

¹Columbia University, New York, NY, USA. ²University of Florida, Gainesville, FL, USA

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

Psychosocial Impacts of EA-PGS among Students, Parents of students, and Educators

Lucas Matthews

Columbia University, New York, USA

**Public Science Presentation

Reducing Beliefs in Genetic Essentialism Using the Humane Genetics Curriculum

Robbee Wedow¹, Andrew Brubaker², Monica Weindling², Kathryn Malerbi¹, Yeongmi Jeong¹, Katherine Thompson¹, Brian Donovan²

¹Purdue University, West Lafayette, USA. ²University of Colorado Boulder, Boulder, USA

**Public Science Presentation

 

Brief Break (15 minutes)

14:15 - 14:30 Wednesday, 24th June, 2026
Location: E2 + Foyer

 
Research Talks 1
Gene-by-Environment Interactions for Anxiety and Depression

14:30 - 15:45 Wednesday, 24th June, 2026
Location: Uva 1-2
Chair: TBA

Identifying differential interactions of traumatic experiences with genetic risk for posttraumatic stress disorder

Jonathan Coleman^1,2, Jacob Knyspel¹, Saakshi Kakar^1,2, Anna Carnegie¹, Gursharan Kalsi¹, Laura Meldrum^1,2, Iona Smith¹, Shannon Bristow¹, Molly Davies¹, Chérie Armour³, Thalia Eley^1,2, Gerome Breen^1,2, Chloe Wong^1,2

¹Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, London, United Kingdom. ²National Institute for Health and Care Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Trust, London, United Kingdom. ³Stress, Trauma, and Related Conditions (STARC) Research Centre, School of Psychology, Queen’s University Belfast, Belfast, United Kingdom

Clarifying the relationship between smoking and stress: triangulation of evidence from causally informative methods

Tessa A. Zonneveld, Adrià Túnez, Rada R. Veeneman, Eva Lukas, Anaïs B. Thijssen, Margot P. van de Weijer, Jorien L. Treur

Genetic Epidemiology, Department of Psychiatry, Amsterdam UMC, location University of Amsterdam, Amsterdam, Netherlands

**Early Career Presentation

Social connection can mitigate depression risk

Katherine Thompson¹, Shawn Bauldry¹, Elisabeth Noland², Evelina Akimova¹, Erin Dunn¹, Yeongmi Jeong¹, Geyu Zhou¹, Moritz Herle³, Robbee Wedow^1,4

¹Purdue University, West Lafayette, USA. ²niversity of Illinois Chicago, Chicago, USA. ³King's College London, London, United Kingdom. ⁴Indiana University School of Medicine, Indianapolis, USA

**Community, Accessibility, & Growth Presentation

Social Anxiety: Is it in Your Genes or Just Your ZIP Code?

Regan T Harle, Rachel L Kember

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA

**Community, Accessibility, & Growth Presentation

The clinician as an environmental exposure: nationwide variation in depression diagnosis

Ziada Ayorech, Mathias Valstad, Perline Demange, Rosa Cheesman, Ludvig Bjørndal, Espen Eilertsen, Eivind Ystrøm

University of Oslo, Oslo, Norway

The genetic overlap between anxiety and cardiovascular disease differs by arrhythmic and non-arrhythmic subtypes

Eva Lukas¹, Vaishvi Agrawal¹, Anne Snijder¹, Sonia Shah², Connie Bezzina³, Anil Ori¹, Dirk Smit¹, Jorien Treur¹

¹Department of Psychiatry, Amsterdam UMC, Amsterdam, Netherlands. ²Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Australia. ³Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam UMC, Amsterdam, Netherlands

 

Research Talks 2
Physical Health and Ageing

14:30 - 15:45 Wednesday, 24th June, 2026
Location: Uva 3-4
Chair:TBA

The Shared Genetic Landscape between Neuropsychiatric Conditions and Brain Cortical Structure

Yuankai He¹, Amir Ebneabbasi¹, Yuanjun Gu¹, Clara M.L. Riegis¹, Bess Pearson², Renato Polimanti³, Jakob Grove⁴, Anders D. Borglum⁴, Duncan Astle¹, Tim Rittman¹, Naomi Wray⁵, Hyejung Won⁶, Richard A.I. Bethlehem¹, Edward T. Bullmore⁷, Varun Warrier¹

¹University of Cambridge, Cambridge, United Kingdom. ²Imperial College, London, United Kingdom. ³Yale University, New Haven, USA. ⁴Aarhus University, Aarhus, Denmark. ⁵University of Oxford, Oxford, United Kingdom. ⁶University of North Carolina, Chapel Hill, USA. ⁷King's College London, London, United Kingdom

**Early Career Presentation

Genetic factors explain delayed incidence of CVD in Intergenerational Transmission of Longevity

Pedro Sant' Anna Barbosa Ferreira¹, Stella Trompet¹, Eline Slagboom^1,2, Joris Deelen^1,2, Marian Beekman¹, Niels van den Berg¹

¹LEIDEN UNIVERSITY MEDICAL CENTER, LEIDEN, Netherlands. ²Max Planck Institute for Biology of Aging, Cologne, Germany

**Early Career Presentation

Diurnal Cortisol from Middle Childhood to Adolescence: Similarities and Differences in Genetic and Environmental Influences

Christy Bui, Leah Doane, Sierra Clifford, Kathryn Lemery-Chalfant

Arizona State University, Tempe, USA

**Early Career Presentation

Genomes, Steps, and Symptoms: Toward Genetically Informed Physical Activity Targets

Julia Sealock^1,2, Benjamin Neale^1,2, Karmel Choi^2,1,3

¹Massachusetts General Hospital, Boston, MA, USA. ²Broad Institute of MIT & Harvard, Cambridge, MA, USA. ³Harvard Medical School, Boston, MA, USA

PRS-wide association study analysis provides insight into the genetic background of hormone sensitivity-related diagnoses in women

Anastasiia Bratchenko, Merli Koitmäe, Jelisaveta Džigurski, Reedik Mägi, Kristi Läll, Triin Laisk

Institute of Genomics, University of Tartu, Tartu, Estonia

**Community, Accessibility, & Growth Presentation

Characterizing Alzheimer’s disease risk in midlife: Associations among plasma biomarkers, epigenetic aging, and cognition in twins

Sophie A. Bell¹, Christopher R. Beam², Ebrahim Zandi², Alyssa C. Kam², Deborah Finkel^2,3, Deborah W. Davis⁴, Eric Turkheimer¹

¹University of Virginia, Charlottesville, USA. ²University of Southern California, Los Angeles, USA. ³Jönköping University, Jönköping, Sweden. ⁴University of Louisville School of Medicine, Louisville, USA

**Early Career Presentation

 

Research Talks 3
Lifestyle, Inequality, and Well-Being

14:30 - 15:45 Wednesday, 24th June, 2026
Location: Erasmus 1
Chair: TBA

GWAS meta-analysis in more than 500,000 Europeans identifies genetic loci for stressful life events and their causal links with neuropsychiatric and cardiometabolic disorders

Haixia Gu^1,2, Wenyu Huang³, Felix Reichelt³, Alireza Ani³, Ilja M. Nolte³, Rujia Wang⁴, Chao Chen^1,5, Catharina A. Hartman², Harold Snieder³

¹MOE Key Laboratory of Rare Pediatric Diseases & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, and Department of Psychiatry, The Second Xiangya Hospital, Central South University, Hunan, China. ²Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands. ³Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands. ⁴Social, Genetic, and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology and Neuroscience; King's College London, Denmark Hill, Camberwell, Groningen, Netherlands. ⁵Furong Laboratory, Hunan, China

**Early Career Presentation

Building life satisfaction from the bottom up or the top down? Testing competing models using genetically informative designs

Dirk Pelt^1,2, Meike Bartels^1,2

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam, Netherlands

The world as I see it: genetic and environmental influences on positive world beliefs and their relationship with social well-being and past mental health

Sophie Perizonius^1,2, Laura W. Wesseldijk^1,2,3, Fredrik Ullén^1,2, Miriam A. Mosing^1,2,4

¹Max Planck for empirical Aesthetics, Frankfurt, Germany. ²Karolinska Institutet, Stockholm, Sweden. ³Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. ⁴Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Melbourne, Australia

**Early Career Presentation

Genetic correlates of residential mobility in Finland: Social stratification, mental health, and the life course

Henrik Dobewall¹, Timo Kauppinen¹, Nayara Machado², Charles Ng’iendo², Maria Vaalavuo¹, Abdel Abdellaoui³, Aleksi Karhula²

¹Finnish Institute for Health and Welfare, Helsinki, Finland. ²University of Turku, Turku, Finland. ³Amsterdam UMC, Amsterdam, Finland

Data-driven dissection of genome-brain associations implicates lifestyle and environment.

Lennart Oblong^1,2, Nicoló Trevisan^1,2, Sourena Soheili-Nezhad^1,2, Yingjie Shi^1,2, Christian F Beckmann^1,2, Emma Sprooten^1,2

¹Radboud University Medical Center, Nijmegen, Netherlands. ²Donders Institute, Nijmegen, Netherlands

**Public Science Presentation

Inequality Across Millennia: Insights from Ancient Genomes

Aysu Okbay¹, Sjoerd van Alten², Kassandra Pomper², Anais Thijsen¹, Abdel Abdellaoui¹

¹Amsterdam UMC, Amsterdam, Netherlands. ²Vrije Universiteit Amsterdam, Amsterdam, Netherlands

**Community, Accessibility, & Growth Presentation

 

Research Talks 4
Externalizing

14:30 - 15:45 Wednesday, 24th June, 2026
Location: Erasmus 2
Chair: TBA

Causal associations between tobacco smoking and mental health: pathways of genetic risk through addiction and socioeconomics

Adrià Túnez^1,2,3, Joëlle A. Pasman¹, Anil P. S. Ori¹, Abdel Abdellaoui¹, Dirk J. A. Smit¹, Jorien L. Treur¹, Karin J. H. Verweij¹

¹Genetic Epidemiology, Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam University Medical Centre, Amsterdam, Netherlands. ³Amsterdam Neuroscience Research Institute, Amsterdam University Medical Centre, Amsterdam, Netherlands

**Early Career Presentation

Growing up with parents who smoke: Genetic and environmental effects on offspring substance use and externalizing psychopathology from a 20-year Minnesota study of adoptive families

Kathryn P. O'Donnell¹, Xinyu Xie¹, Brooke Huizenga¹, Alexander Herman¹, Emily A. Willoughby¹, James J. Lee¹, Robert F. Krueger¹, Sylia Wilson², Glenn I. Roisman², Monica Luciana¹, William G. Iacono¹, Steve Malone¹, Matt McGue¹, Scott Vrieze¹

¹Department of Psychology, University of Minnesota Twin Cities, Minneapolis, USA. ²Institute of Child Development, University of Minnesota Twin Cities, Minneapolis, USA

**Early Career Presentation

Parents' externalizing behavior and children’s human capital

Sjoerd van Alten, Sander de Vries

Vrije Universiteit Amsterdam, Amsterdam, Netherlands

358 Anxiety Polygenic Scores and Adolescent Alcohol Use: Impulsivity and Anxiety Behavioral Pathways among Black, Hispanic/Latinx, and White Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study

Belal Jamil¹, Jinni Su¹, Lanli Jiang¹, Kathryn Lemery-Chalfant¹, Kit Elam², Eleanor Seaton³

¹Arizona State University, Tempe, USA. ²Indiana University, Bloomington, USA. ³University of Illinois Urbana-Champaign, Champaign, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

370 Interplay between Polygenic Risk and Digital Screen Use Behaviors in Predicting Adolescent Alcohol Use

Jinni Su¹, Belal Jamil¹, Lanli Jiang¹, Kit Elam², Eleanor Seaton³, Kathryn Lemery-Chalfant¹, Kevin Grimm¹

¹Arizona State University, Tempe, USA. ²Indiana University, Bloomington, USA. ³University of Illinois Urbana-Champaign, Champaign, USA

**Community, Accessibility, & Growth Presentation

372 Prenatal substance use moderates the etiology of adolescent dysregulation

Amanda Ramos, Maria Balaceanu, Joana Amankwaa

Utah State University, Logan, USA

 

Tea Break (30 minutes)

15:45 - 16:15 Wednesday, 24th June, 2026
Location: E2 + Foyer

 

Full Symposium 9
Examining the Genetic and Biobehavioral Correlates of Neurodevelopmental Phenotypes

16:15 - 17:30 Wednesday, 24th June, 2026
Location: Uva 1-2 
Chair: Lukas Schaffer
Discussant: Daniel Gustavson

Disentangling the links between atypical neurodevelopment and immune-related conditions: A causal triangulation approach.

Christina Dardani^1,2, Alejandra Martinez Sanchez³, Laura Hegemann³, Elizabeth C. Corfield¹, Helga Ask³, Laurie Hannigan⁴, Dheeraj Rai⁵, Renee Gardner⁶, Golam M. Khandaker¹, James W. Dodd¹, Evie Stergiakouli¹, George Davey Smith¹, Robyn Wootton¹, Alexandra Havdahl³

¹University of Bristol, Bristol, United Kingdom. ²Lovisenberg Diakonale Hospital, Oslo, Norway. ³PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ⁴PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, United Kingdom. ⁵University of Bristol, Bristol, Sweden. ⁶Karolinska Institutet, Stockholm, Sweden

Familial and Individual Brain Differences Associated with Attention Problems in Twins

Chloe McGhee-Deakin^1,2, Anika Lindley², Lydia Rader¹, Harry Smolker³, Naomi Friedman^1,2

¹Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, USA. ²Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, USA. ³Institute of Cognitive Science, University of Colorado Boulder, Boulder, USA

**Early Career Presentation

Is there a general genetic “n” factor underlying neurodevelopmental conditions?

Morgan Morgan¹, Margherita Malanchini², Angelica Ronald¹

¹School of Psychology, Faculty of Health & Medical Sciences, The University of Surrey, Guildford, United Kingdom. ²School of Biological and Behavioural Sciences, Queen Mary University of London, London, United Kingdom

**Early Career Presentation

Multivariate Genome-Wide Analysis of Interpersonal Functioning and its Overlap with Neurodevelopmental and Psychiatric Liability

Lukas Schaffer, Kristen Kelly, Jeremy Lawrence, Sophie Breunig, Luke Conrad, Alexander Shepphard, Andrew Grotzinger

University of Colorado Boulder, Boulder, USA

**Early Career Presentation

 

Full Symposium 10:
Global Psychiatric Genomics: Expanding Representation and Refining Genetic Archetecture Across Populations

16:15 - 17:30 Wednesday, 24th June, 2026
Location: Uva 3-4
Chair: Madhurbain Singh
Discussant: Roseann Peterson

Trans-ancestry Genome-wide Association Meta-analysis of Depression Diagnosis Across 500,000 Cases and 2 Million Controls: Results from the PsycheMERGE Network Diversity Initiative

Madhurbain Singh^1,2, Chris Chatzinakos^3,2, Peter Barr^3,4, Joanna Biernacka^5,6, Christopher Chabris⁷, Kyra Feuer⁸, Mischa Lundberg^9,10, Maria Niarchou¹¹, Aditya Pimplaskar¹², Jette Steinbach¹³, Ellen Tsai^14,11, Zhenyi Wu^{15,16,17,14,18,19}, Yuanxin Zhong²⁰, Rachel Kember^8,21, Roseann Peterson^3,2

¹Social Genetic and Developmental Psychiatry Centre, King’s College London – Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom. ²Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA. ³Department of Psychiatry and Behavioral Sciences, Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, NY, USA. ⁴Department of Community Health Sciences, School of Public Health, SUNY Downstate Health Sciences University, Brooklyn, NY, USA. ⁵Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA. ⁶Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. ⁷Department of Bioethics and Decision Sciences, Geisinger Clinic, Danville, PA, USA. ⁸Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA. ⁹Institute of Biological Psychiatry, Mental Health Center - Sct Hans, Copenhagen University Hospital - Mental Health Services CPH, Copenhagen, Denmark. ¹⁰The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Copenhagen, Denmark. ¹¹Department of Medicine, Division of Genetic Medicine, Vanderbilt University, Nashville, TN, USA. ¹²Bioinformatics Interdepartmental Program, University of California - Los Angeles, Los Angeles, CA, USA. ¹³National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark. ¹⁴Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ¹⁵Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ¹⁶Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ¹⁷Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ¹⁸Mental Illness Research, Education, and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, USA. ¹⁹Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY, USA. ²⁰Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. ²¹Crescenz VA Medical Center, Philadelphia, PA, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

Characterizing the polygenic profile of reproductive-related affective disorders in an East Asian population

Jolien Rietkerk^1,2,3, Madhurbain Singh⁴, Dana Lapato³, Peter Barr², Christos Chatzinakos², Tim Bigdeli², Kenneth S. Kendler³, Hanna M. van Loo¹, Roseann E. Peterson^2,3

¹Universitair Centrum Psychiatrie, Universitair Medisch Centrum Groningen, Groningen, Netherlands. ²Institute for Genomics in Health, Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA. ³Virginia Institute of Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA. ⁴Department of Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom

**Community, Accessibility, & Growth Presentation

SCHEMA 2.0: Exome Sequencing Reveals New Genetic Contributors to Schizophrenia

Julia Sealock¹, Daniel Howrigan¹, Benjamin Neale¹, Mark Daly¹, on behalf of the SCHEMA consortium²

¹Massachusetts General Hospital, Boston, USA. ²Broad Institute, Cambridge, USA

**Community, Accessibility, & Growth Presentation

348 Serious Mental Illness Genetics in a Colombian Founder Population: The Misión Origen Biobank

Loes Olde Loohuis¹, on behalf of Misión Origen collaborators²

¹UCLA, Los Angeles, USA. ²University of Antioqua, UCLA,, Medellin, Colombia

**Community, Accessibility, & Growth Presentation

 

Full Symposium 11:
Capturing Liability to Complex Health Outcomes Through Family History Assessments

16:15 - 17:30 Wednesday, 24th June, 2026
Location: Erasmus 1
Chair: Emma Pruin
Discussant: Andrew Schork

Comparing family history indicators and polygenic scores for depressive disorder in the NESDA study

Emma Pruin^1,2, Yuri Milaneschi^1,2,3, Meike Bartels^4,2, Pietro Bassani¹, Brenda Penninx^1,2,3, Wouter Peyrot^1,2

¹Dept. of Psychiatry, Amsterdam UMC, Amsterdam, Netherlands. ²Amsterdam Public Health, Amsterdam, Netherlands. ³Amsterdam Neuroscience, Amsterdam, Netherlands. ⁴Dept. of Biological Psychology, Vrije Universiteit, Amsterdam, Netherlands

**Early Career Presentation

Family records and molecular genotypes as complementary sources of genetic liability for psychiatric disorders

Morten Dybdahl Krebs¹, Kajsa-Lotta Georgii Hellberg¹, Mischa Lundberg¹, Henrik Ohlsson², Emil Pedersen³, Jette Steinbach³, Sonja LaBianca¹, Andres Ingason¹, Alfonso Buil¹, Thomas M Werge¹, Bjarni J Vilhjalmsson³, Jonathan Flint⁴, Silviu Bacanu⁵, Kenneth S Kendler⁵, Andrew J. Schork¹

¹Institute of Biological Psychiatry, Roskilde, Denmark. ²Center for Primary Health Care Research, Lund University, Malmö, Sweden. ³National Centre for Register-Based Research, Business and Social Sciences, Aarhus University, Aarhus, Denmark. ⁴Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA. ⁵Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA

The effect of family history and polygenic risk scores on general and abdominal obesity in the Lifelines Cohort Study

Rujia Wang¹, Catharina Hartman², Peter Visscher^3,4, Harold Snieder¹

¹Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ²Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ³Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. ⁴Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia

Effects of Family Genetic Risk Scores and Environmental Factors on Risk of Schizophrenia and Bipolar Disorder

Sarah Bergen¹, Natassia Robinson¹, Alexander Ploner¹, Henrik Ohlsson², Paul Lichtenstein¹, Kenneth Kendler³

¹Karolinska Institute, Stockholm, Sweden. ²Lund University, Malmo, Sweden. ³Virginia Commonwealth University, Richmond, USA

 

Full Symposium 12:
Exploring Gene-Environment Interaction and Correlation Using Multiple Methods in the MoBa and Norwegian Registry Data

16:15 - 17:30 Wednesday, 24th June, 2026
Location: Erasmus 2
Chair: Tom McAdams
Discussant:Tom McAdams

The role of the socioeconomic context in moderating genetic and environmental transmission of mental health risk

Jessie R. Baldwin¹, Tom A. McAdams²

¹University College London, London, United Kingdom. ²King's College London, London, United Kingdom

Gene-environment Interaction in the Diagnosis and Treatment of ADHD

Sverre Ofstad¹, Perline Demange¹, Mathias Valstad¹, Eivind Ystrom^1,2

¹University of Oslo, Oslo, Norway. ²Norwegian Institute of Public Health, Oslo, Norway

**Early Career Presentation

An indirect genetic approach to peer effects in education

Espen Moen Eilertsen, Eivind Ystrom

UiO, Oslo, Norway

Child Personality Polygenic Indices and Parental Distress: Evidence of Active Gene-Environment Correlations and Interactions from Parent–Offspring Trios

Eivind Ystrøm^1,2, Ziada Ayorech¹, Ludvig D. Bjørndal¹, Clara Timpe¹, Rosa Cheesman¹, Espen M. Eilertsen¹, Tom A. McAdams³, Perline Demange¹

¹University of Oslo, Oslo, Norway. ²Norwegian Institute of Public Health, Oslo, Norway. ³King's College London, London, United Kingdom

 

Poster Session 1 and Reception

17:30 - 19:00 Wednesday, 24th June, 2026
Location: E2 + Foyer

W1. Interplay of Genes and Environment across Multiple Studies (IGEMS): Cohort Description

Deborah Finkel^1,2, Brian K. Finch¹, Margaret Gatz¹, Susan E. Luczak¹, Jenae M. Neiderhiser³, Chandra A. Reynolds^4,5, Nancy L. Pedersen⁶

¹University of Southern California, Los Angeles, USA. ²Jönköping University, Jönköping, Sweden. ³Pennsylvania State University, University Park, USA. ⁴University of Colorado, Boulder, USA. ⁵University of California Riverside, Riverside, USA. ⁶Karolinska Institutet, Stockholm, Sweden

W2. International Statistical Genetics Workshop Online Learning Hub

Dinka Smajlagic¹, Madhurbain Singh², Jeffrey M. Lessem¹, Sarah Medland³, Abdel Abdellaoui⁴, Hermine H. Maes⁵, Matthew Keller¹

¹Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, USA. ²Social Genetic and Developmental Psychiatry Centre, King’s College London, London, United Kingdom. ³Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston, Australia. ⁴Department of Psychiatry, Amsterdam UMC, Amsterdam, Netherlands. ⁵Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

W3. Raising awareness of the Research Master's Genes in Behaviour and Health in Amsterdam

Bruno Sauce, Wonu Akingbuwa, Jenny van Dongen

Vrije Universiteit Amsterdam, Amsterdam, Netherlands

**Public Science Presentation

W4. GERTRUD: Germany’s New Twin Registry for Longitudinal Genetic and Environmental Research

Moana Beyer^1,2, GERTRUD consortium¹, Simone Kühn^1,3,4,5

¹Max Planck Institute for Human Development, Berlin, Germany. ²Humboldt University, Berlin, Germany. ³University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ⁴Charité – Universitätsmedizin Berlin, Berlin, Germany. ⁵Max Planck UCL Centre for Computational Psychiatry and Ageing Research, London, United Kingdom

W5. The Behavior Genetics Association Early Career Network: Supporting the next generation of behavior geneticists

Fiona A. Hagenbeek¹, Sophie A. Bell², Sarah L. Carroll³, LiChen Dong⁴, Amy Loviska⁵, Li Hazel Yu⁵, Stephanie Zellers⁶, Chandra A. Reynolds³, Emma C. Johnson⁷

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²University of Virginia, Charlottesvill, USA. ³University of Colorado Boulder, Boulder, USA. ⁴University of Wisconsin-Madison, Madison, USA. ⁵Purdue University, West Lafayette, USA. ⁶University of Helsinki, Helsinki, Finland. ⁷Washington University School of Medicine, St Louis, USA

W6. Twin Registries Worldwide and Population-Level Data Linkages

Dmitry Kuznetsov¹, Veronika Odintsova^2,3, Dorret Boomsma^2,3

¹Max Planck Institute for Human Development, Center for Environmental Neuroscience, Berlin, Germany. ²Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ³Amsterdam Reproduction and Development Research Institute, Amsterdam, Netherlands

W7. What Is the Field Ready For? Building a Global Extended Twin and Family Initiative

Meike Bartels¹, Chris Beam², Elizabeth Prom-Wormley³, Scott Vrieze⁴, Sarah Medland⁵, Hermine Maes³, Brad Verhulst⁶, Neil Davies⁷, Patrick Turley², Matt Keller⁸

¹Vrije Universiteit, Amsterdam, Netherlands. ²University of Southern California, Los Angeles, USA. ³Virginia Commonwealth University, Richmond, USA. ⁴University of Minnesota, Minneapolis, USA. ⁵QIMR Berghofer Medical Research Institute, Brisbane, Australia. ⁶Texas A&M University, Houston, USA. ⁷University College London, London, United Kingdom. ⁸Institute for Behavioral Genetics, Boulder, USA

**Community, Accessibility, & Growth Presentation

W8. Responding to the Call: Proposed Strategies to Develop a Global Extended Twin and Family (ETF) Biobank

Matthew Keller

University of Colorado Boulder, Boulder, USA

W9. Depression Prediction at Scale: Comparing Statistical and Machine Learning Models Across U.S. Cohorts

Rafael Geurgas¹, Evelina T Akimova^1,2,3, Yeongmi Jeong¹, Saranya Arirangan¹, Kathryn Fiuza Malerbi^1,4, Katherine N Thompson¹, Robbee Wedow^1,5

¹Department of Sociology, Purdue University, West Lafayette, USA. ²Department of Statistics, Purdue University, West Lafayette, USA. ³Center on Aging and the Life Course, Purdue University, West Lafayette, USA. ⁴Department of Public Health, Purdue University, West Lafayette, USA. ⁵Department of Medical and Molecular Genetics, Indiana University School, Indianapolis, USA

W10. From risk to prodrome: depression timing and polygenic risk in late-onset dementia

Triinu Ojalo^1,2, Kadri Kõiv¹, Nele Taba¹, Kelli Lehto¹

¹University of Tartu, Tartu, Estonia. ²Tallinn Children's Hospital, Tallinn, Estonia

W11. Dissecting Phenotypic and Genotypic Similarity of Depression and Anxiety Symptoms across Scales

Robyn Wootton^1,2,3, Esme Elsden⁴, Sally Marshall⁴, Floris Huider⁵, Mark Adams⁴, Jackson Thorp⁶, Alex Kwong⁴, Johanne Hagen Pettersen^2,7, Helga Ask^8,2, Alex Havdahl^2,9,10, Laurie Hannigan^9,2, Na Cai¹¹

¹The School of Psychology and Neuroscience, University of Bristol, Bristol, United Kingdom. ²PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ³MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ⁴Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom. ⁵Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁶School of Biological Sciences, University of Queensland, Brisbane, Australia. ⁷Centre for Precision Psychiatry, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. ⁸Department of Child Health and Development, Norwegian Institute of Public Health, Oslo, Norway. ⁹Research Department, Lovisenberg Diakonale Hospital, Oslo, Norway. ¹⁰PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. ¹¹Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland

W12. Sex differences in genetic pathways underlying ischaemic heart disease–depression comorbidity

Cato Romero^1,2, Alexey Shadrin³, Nadine Parker³, Sara Stinson³, Linn Rødevand³, Dennis van der Meer³, Kevin O'Connell³, Eva van Walree^4,5, Jeanne Savage², Danielle Posthuma^1,2, Ole Andreassen³, Sophie van der Sluis^1,2

¹Department of Child and Adolescent Psychiatry and Psychology, Section Complex Trait Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam UMC, Amsterdam, Netherlands. ²Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ³Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway. ⁴Emma Center for Personalized Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands. ⁵Department of Human Genetics, Amsterdam Reproduction & Development, Amsterdam University Medical Center, Amsterdam, Netherlands

**Early Career Presentation

W13. Multi-cohort comparison of polygenic score for major depressive disorder association with trajectories of depressive symptoms across the life course

Esme Elsden, Poppy Grimes, Paul Craig, Sam Bentwood, Andrew McIntosh, Alex S. F. Kwong

Division of Psychiatry, Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, United Kingdom

W14. Adverse childhood experiences and severe mental health conditions in early adulthood: a twin study

Xinyu Meng¹, Giacomo Bignardi¹, Jessie Baldwin², Andrea Danese¹, Thalia Eley¹, Chloe Wong¹, Tom McAdams¹

¹King's College London, London, United Kingdom. ²University College London, London, United Kingdom

W15. Disentangling the confounding relationships in gene-environment interactions in schizophrenia

Laurie Haig¹, Isabella Badini¹, Jennifer Dykxhoorn¹, Neil M Davies^1,2,3

¹Division of Psychiatry, University College London, London, United Kingdom. ²Department of Statistical Science, University College London, London, United Kingdom. ³Norwegian University of Science and Technology, Trondheim, Norway

W16. Separating the association of trauma from schizophrenia and bipolar using genomic structural equation modelling

Aoife Coghlan, Angelica Ronald

University of Surrey, Guildford, United Kingdom

**Early Career Presentation

W17. The role of sex hormones in severe mental illness: a genetic exploration.

Rada R. Veeneman¹, Karin J. H. Verweij¹, Iris E. C. Sommer², Jorien L. Treur¹, Jentien M. Vermeulen³

¹Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Genetic Epidemiology, Amsterdam, Netherlands. ²University Center of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands. ³Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam, Netherlands

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

W18. Gene-Environment Interaction Study of Early Life Family Warmth and Midlife Symptoms of Paranoia

Maria Tirado Arias^1,2, Christopher. R Beam^1,2, Ebrahim Zandi¹, Deborah Finkel³, Deborah W. Davis⁴, Eric Turkheimer⁵

¹Department of Psychology, University of Southern California, Los Angeles, USA. ²Leonard Davis School of Gerontology, University of Southern California, Los Angeles, USA. ³USC Dornsife College of Letters and Sciences, Los Angeles, USA. ⁴University of Louisville School of Medicine, Department of Pediatrics, Louisville, USA. ⁵Department of Psychology, University of Virginia, Charlottesville, USA

W19. Causal Effects of Cannabis Use on Depression and Psychosis: Triangulating Genetic and Observational Methods

Joëlle Pasman¹, Adria Tunez¹, Tessa Zonneveld¹, Laura Wesseldijk¹, Sinan Marsden¹, Margreet ten Have², Annemarie Luik², Bart Rutten³, Sinan Gülöksüz⁴, Jim van Os⁵, Penelope Lind⁶, Nicholas Martin⁶, Jorien Treur¹, Karin Verweij¹

¹Amsterdam UMC location University of Amsterdam, Department of Psychiatry,, Amsterdam, Netherlands. ²Netherlands Institute of Mental Health and Addiction, Utrecht, Netherlands. ³Department of Psychiatry and Neuropsychology, Division of Cellular Neuroscience, University of Maastricht, Maastricht, Netherlands. ⁴Department of Psychiatry and Psychology, Maastricht University Medical Centre, Maastricht, Netherlands. ⁵Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, Netherlands. ⁶QIMR Berghofer Medical Research Institute, Translational Neurogenomics Laboratory, Brisbane, Australia

W20. Familial Co-aggregation of Substance Use Disorders and Criminal Convictions Across Neighborhood Social Structures: A Nationwide Swedish Cohort Study

Anneli Andersson, Sofi Oskarsson, Brittany Evans

Örebro University, Örebro, Sweden

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

W21. Familial Transmission of Substance Use Disorders: An Analysis of Over 1800 Nuclear Twin Families

Brooke Huizenga¹, Jordan Alexander¹, Robert Krueger¹, Gretchen Saunders¹, Emily Willoughby¹, Sylia Wilson¹, Stephanie Zellers², Matt McGue¹, Scott Vrieze¹

¹University of Minnesota, Minneapolis, USA. ²University of Helsinki, Helsinki, Finland

**Early Career Presentation

W22. Creativity and Substance Use: A Systematic Review from Anecdotal Evidence to Genetically Informed Studies

Parnian Poursafa^1,2, Vivien Vach¹, Laura W. Wesseldijk^1,2,3, Karin J.H. Verweij³, Fredrik Ullén^1,2, Miriam A. Mosing^1,2,4,5

¹Department of Neuroscience, Karolinska Institute, Stockholm, Sweden. ²Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany. ³Department of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands. ⁴Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden. ⁵Melbourne School of Psychological Sciences, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Melbourne, Australia

**Early Career Presentation

W23. Investigating sex differences in the genetic architecture of posttraumatic stress disorder and substance use disorders within the Swedish registries

Emily Notari¹, Sara Lönn, Ph.D.², Kenneth Kendler, M.D.¹, Hermine Maes, Ph.D.¹, Jan Sundquist, M.D., Ph.D.², Kristina Sundquist, M.D., Ph.D.², Ananda Amstadter, Ph.D.¹

¹Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA. ²Center for Primary Health Care Research, Lund University, Malmö, Sweden

**Early Career Presentation

W24. Multi-Ancestral Sex-Stratified GWAS Meta-Analysis of Substance Use Disorders in over 2.2 Million Individuals

Jared V Balbona^1,2, Pamela N Romero-Villela³, Margaret L Clapp Sullivan³, Laura Vilar-Ribó⁴, Jimmy Hart², Jeanne E Savage⁵, Ellen L Tsai⁶, Sandra Sanchez-Roige^4,7,8, Dongbing Lai⁹, Rachel Kember¹⁰, Alex P Miller¹¹, Howard J Edenberg¹², Joel Gelernter^13,14,15,16, Arpana Agrawal³, Emma C Johnson³

¹Virginia Commonwealth University, Richmond, VA, USA. ²Virginia Institute for Psychiatric and Behavioral Genetics, Richmond, VA, USA. ³Department of Psychiatry, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA. ⁴Department of Psychiatry, University of California San Diego, La Jolla, CA, USA. ⁵Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁶Department of Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ⁷Institute for Genomic Medicine, University of California San Diego, San Diego, CA, USA. ⁸Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. ⁹Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA. ¹⁰Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ¹¹Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA. ¹²Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA. ¹³Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. ¹⁴Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA. ¹⁵Department of Genetics, Yale School of Medicine, New Haven, CT, USA. ¹⁶Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA

**Community, Accessibility, & Growth Presentation

W25. Participants as Partners: Application of Group Concept Mapping to Characterize  Substance Use Resistance Factors in a Twin Sample

Badi I Quinteros Espinoza¹, Hermine H.M. Maes¹, Kelci Straka-Mai², Courtney Blondino³, Michael M. Vanyukov⁴, Levent Kirisci⁴, Emily Zimmerman², The Mid-Atlantic Twin Registry The Mid-Atlantic Twin Registry⁵, Caleb Bridgwater², Chao-Yi Lo², Lubidia Menjivar², Aarushi Patel², Cate Vaughn², Sunday Wright², Elizabeth Prom-Wormley²

¹Virginia Commonwealth University Department of Cellular, Molecular and Genetic Medicine, Richmond, USA. ²Virginia Commonwealth University Department of Epidemiology, Richmond, USA. ³University of Richmond Department of Global Health, Richmond, USA. ⁴University of Pittsburgh Department of Pharmaceutical Sciences, Pittsburgh, USA. ⁵Virginia Commonwealth University Office of the Vice President of Research, Richmond, USA

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

W26. Rare variant exome sequencing meta-analysis across All of Us (AoU), UK Biobank (UKB) and Trans-Omics for Precision Medicine Initiative (TOPMed)

Sarah Hauryski¹, Jordan Alexander¹, Seon-Kyeong Jang², Dajiang Liu³, Gretchen Saunders¹, Scott Vrieze¹

¹University of Minnesota, Minneapolis, USA. ²University of California, Los Angeles, Los Angeles, USA. ³Pennsylvania State University College of Medicine, Hershey, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

W27. Disentangling the links between socioeconomic status and alcohol use disorder: evidence from a co-twin control study

Gianna Rea-Sandin¹, Jonathan Schaefer², Jaylen Santos¹, Matt McGue¹, Scott Vrieze¹, Sylia Wilson¹

¹University of Minnesota, Minneapolis, USA. ²Vanderbilt University, Nashville, USA

W28. Identifying risk factors for adult-onset psychiatric disorders in adolescents with anxiety

Charlotte Dennison^1,2, Amy Shakeshaft^1,2, Lucy Riglin^1,2, Frances Rice^1,2, Ole Andreassen³, Helga Ask^4,5, Alexandra Havdahl^4,5,6, Joanna Martin^1,2, Daniel Pine⁷, Anita Thapar^1,2

¹Wolfson Centre for Young People's Mental Health, Cardiff University, Cardiff, United Kingdom. ²Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, United Kingdom. ³Centre for Precision Psychiatry, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. ⁴PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ⁵PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. ⁶Research Departement, Lovisenberg Diakonale Hospital, Oslo, Norway. ⁷Emotion and Development Branch, National Institute of Mental Health, Bethesda, MD, USA

W29. Bidirectional associations between pain, anxiety, and depressive symptoms during adolescence: Findings from the Quebec Newborn Twin Study

Thi Viet Hai Tran¹, Geneviève Morneau-Vaillancourt², Ginette Dionne³, Mara Brendgen⁴, Frank Vitaro⁵, Faith Matcham¹, Kathryn J. Lester¹, Marco Battaglia⁶, Amélie Petitclerc³, Isabelle Ouellet-Morin², Michel Boivin³, Ellen J. Thompson¹

¹School of Psychology, Faculty of Science, Engineering and Medicine, University of Sussex, Falmer, Sussex, United Kingdom. ²School of Criminology, University of Montreal and the Research Center of the Montreal Mental Health University Institute, Montreal, Canada. ³School of Psychology, Laval University, Quebec, Canada. ⁴Department of Psychology, University of Quebec in Montreal, Montreal, Canada. ⁵University of Montreal, Montreal, Canada. ⁶Department of Psychiatry, University of Toronto, Toronto, Canada

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

W30. Genetic, familial, lifestyle, and environmental factors influence adolescent mental health in an intertwined and reciprocal way

Yingjie Shi^1,2, Nina Roth Mota^1,2, Haowen Su^1,2, Catharina Hartman³, Emma Sprooten^1,2, Barbara Franke^1,2

¹Radboud University Medical Center, Nijmegen, Netherlands. ²Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands. ³Interdisciplinary Center of Psychiatric Epidemiology and Emotion regulation (ICPE), Department of Psychiatry, Groningen, Netherlands

W31. Low Prosociality as a Developmental Marker of Transdiagnostic Liability to Psychopathology

Sophie Sansum¹, Margherita Malanchini^1,2, Robert Plomin²

¹Queen Mary University of London, London, United Kingdom. ²King's College London, London, United Kingdom

**Early Career Presentation

W32. Evaluating modeling approaches for estimating genetic and environmental influences on drug initiation

Cailey Fay, S. Mason Garrison

Wake Forest University, Winston-Salem, USA

**Early Career Presentation

W33. The context-dependent nature of evocative genotype-environment correlation

Sarah Carroll¹, Daniel Gustavson¹, Robin Corley¹, Matthew Keller^1,2, Soo Rhee^1,2, Chandra Reynolds^1,2

¹Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, USA. ²Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, USA

W34. A Study of Evocative Gene-Environment Correlations Among Adolescent Parental Monitoring, Effortful Control, and Externalizing Behaviors

Isabella Davis, Qingyang Liu, Leah Doane, Kathryn Lemery-Chalfant

Arizona State University, Tempe, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

W35. Is Reward Sensitivity Uniquely Predictive of Substance Use Beyond Relations to Externalizing Once Controlling for Cognitive Control in Adolescence?

Analicia Howard, Lydia Rader, Naomi Friedman

University of Colorado Boulder, Boulder, USA

**Early Career Presentation

W36. Testing genetic risk and the dynamics of positive affect in early childhood parent-child interactions on adolescent alcohol use.

Tiffany Tran¹, Alexys Murillo¹, Sierra Clifford¹, Cheuk Hei Cheng¹, Jenn-Yun Tein¹, Daniel Shaw², Kathryn Lemery-Chalfant¹

¹Arizona State University, Tempe, USA. ²University of Pittsburgh, Pittsburgh, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

W37. Genetic and Environmental Contributions to the Association Between Emotion Regulation and Executive Functions

Amy Texter, Naomi Friedman

University of Colorado Boulder, Boulder, USA

**Early Career Presentation

W38. Neighborhood Features Moderate the Etiology of Emotion Regulation During Adolescence

Elizabeth Shewark

University of Notre Dame, Notre Dame, USA

W39. A Longitudinal Analysis of Music Engagement and Externalizing Behavior across Adolescence

Jordan Chow¹, Daniel E. Gustavson², Madhurbain Singh^3,1, Hermine H.M. Maes¹

¹Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA. ²Institute for Behavioral Genetics University of Colorado Boulder, Boulder, USA. ³Social Genetic and Developmental Psychiatry Centre, King’s College London – Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom

**Early Career Presentation

W40. Exploring How Music Engagement Traits Relate to Risk Taking and Impulsivity in Adolescents and Adults: A Co-Sibling Control Study

Lilia Geel^1,2, Lydia Rader², Jarrod Ellingson³, Sylia Wilson⁴, Scott Vrieze⁴, Soo Rhee^1,2, Hermine Maes⁵, Daniel Gustavson^1,2

¹Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, USA. ²Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, USA. ³Department of Psychiatry, University of Colorado Denver, Denver, USA. ⁴Department of Psychology, University of Minnesota Twin Cities, Minneapolis, USA. ⁵Virginia Institute for Psychiatric and Behavioral Genetics, Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University, Richmond, USA

**Early Career Presentation

W41. Testing Heterogeneity in Genetic and Environmental Sources of Variance in Music Engagement by Sex and Age using Twin-Sibling-Parent Modeling of CATSLife Data

Hermine Maes¹, Mei-Hsin Su¹, Naomi Friedman², Robin Corley², Sally Wadsworth², Chandra Reynolds², Daniel Gustavson²

¹Virginia Commonwealth University, Richmond, USA. ²University of Colorado at Boulder, Boulder, USA

W42. Does Polygenic Sensitivity to DNA Methylation Moderate Relations Between Air Pollution and Adolescent Sleep?

Kit Elam¹, Xuelei Xu¹, Patrick Quinn¹, Kathryn Lemery-Chalfant²

¹Indiana University Bloomington, Bloomington, USA. ²Arizona State University, Tempe, USA

**Community, Accessibility, & Growth Presentation

W43. Sex Differences and Rater Effects in Autism Polygenic Score Associations with autistic traits in a General Population

Thomas Sollie, Tinca Polderman, René Pool, Melanie de Wit, Meike Bartels, Wonuola Akingbuwa

Vrije Universiteit, Amsterdam, Netherlands

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

W44. Developmental and Genetic Associations Between Early Motor Skills and Autistic Traits in Boys and Girls

Kassandra A. Pomper¹, Tinca JC Polderman^2,1, Dennis van 't Ent¹, Elsje van Bergen¹

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Amsterdam University Medical Center, Amsterdam, Netherlands

**Early Career Presentation

W45. Mitochondrial Inheritance Reveals Domain-Specific Patterns of ASD Comorbidity

L. Bayavuya Moyakhe¹, S. Mason Garrison², Michael. D Hunter³, Xuanyu Lyu⁴, Nithya Mylakumar¹, S.Alexandra Burt¹

¹Michigan State University, East Lansing, USA. ²Wake Forest University, Winston-Salem, USA. ³Pennsylvania State University, University Park, USA. ⁴University of Colorado at Boulder, Boulder, USA

W46. Phenotypic structure and genetic correlates of adolescent psychiatric symptomatology in versus out of autism.

Taylor Thomas^1,2, Elise Robinson^1,2

¹Massachusetts General Hospital, Boston, USA. ²Broad Institute of MIT and Harvard, Cambridge, USA

W47. Genetic associations between early neurodevelopmental traits and health and functional outcomes over the lifecourse.

Wangjingyi Liao¹, Agnieszka Musial¹, Chiara Caserini¹, Jessica Agnew-Blais¹, Sarah-Naomi James², Angelica Ronald³, Margherita Malanchini^1,4, Giorgia Michelini¹

¹Queen Mary University of London, London, United Kingdom. ²University College London, London, United Kingdom. ³University of Surrey, Guildford, United Kingdom. ⁴Social, Genetic & Developmental Psychiatry, London, United Kingdom

**Early Career Presentation

W48. Trends in ADHD Symptoms and Heritability Estimates Over 30 Years

Sezgi Ercan, Conor Dolan, Dorret Boomsma

Vrije University Amsterdam, Amsterdam, Netherlands

W49. Sex differences in genetic and phenotypic profiles of adult-diagnosed ADHD

Kadri Kõiv¹, Triinu Ojalo^1,2, Triinu Varvas¹, Katri Pärna¹, Kelli Lehto¹

¹Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. ²Psychiatry Clinic, Tallinn Children’s Hospital, Tallinn, Estonia

W50. Exploring the role of binge eating in the association between ADHD and BMI: A twin study

YUAN YOU¹, Tom McAdams¹, Olakunle Oginni², Chaoyu Liu³, Moritz Herle¹, Helena Zavos¹

¹King's College London, London, United Kingdom. ²b. Wolfson Centre for Young People’s Mental Health, Cardiff University, Cardiff, United Kingdom. ³Department of Psychiatry, Yale University, New Haven, USA

W51. Genetic and Environmental Influences on Developmental Trajectories of Activity Level in the Preschool Period

Kimberly Saudino¹, Chang Liu², Mark Yue¹, Jody Ganiban³

¹Boston University, Boston, USA. ²Washington State University, Pullman, USA. ³George Washington University, Washington, USA

 

 
 
Thursday June 25^th 2026

Education Session
Panel Discussion on the Ins and Outs of Publishing

08:00 - 09:00 Thursday, 25th June, 2026
Location: Uva Full

Chair: Brad Verhulst
Panel:

Stephanie Zellers - Institute for Molecular Medicine Finland, University of Helsiki, Helsinki, Finland

Angelica Ronald - Editor of the Journal of Childhood Psychology and Psychiatry; University of Surrey, Guildford, United Kingdom

Michel Nivard - Editor of Psychological Science; University of Bristol, Bristol, United Kingdom

Roseann Peterson - Specialty Chief Editor, Behavioral and Psychiatric Genetics, Frontiers in Genetics; State University of New York Downstate Health Sciences University, Brooklyn, USA

Sarah Medland - Incoming editor of Twin Research and Human Genetics; QIMR, Brisbane, Australia

Valerie Knopik - Editor of Behavior Genetics; Purdue University, West Lafayette, USA

 

Presidential Symposium
Selected Early Career Presenters

09:00 - 10:30 Thursday, 25th June, 2026
Location: Uva Full
Chair: TBA

Polygenic Associations With Educational Attainment in East Versus West Germany: Differences Emerge After Reunification

Deniz Fraemke¹, Yayouk Willems¹, Aysu Okbay², Ulman Lindenberger³, Sabine Zinn^4,5, Gert Wagner³, David Richter⁶, Kathryn P. Harden⁷, Elliot M. Tucker-Drob⁸, Ralph Hertwig³, Phillipp Koellinger², Laurel Raffington¹

¹Max Planck Research Group Biosocial – Biology, Social Disparities, and Development, Max Planck Institute for Human Development, Berlin, Germany. ²School of Business and Economics, Tinbergen Institute, Amsterdam, Netherlands. ³Max Planck Institute for Human Development, Berlin, Germany. ⁴German Socio-Economic Panel Study Department, Berlin, Germany. ⁵Department of Social Sciences, Humboldt University, Berlin, Germany. ⁶Department of Education and Psychology, Freie Universität zu Berlin, Berlin, Germany. ⁷Department of Psychology, The University of Texas,, Austin, USA. ⁸Department of Psychology, The University of Texas, Austin, USA

**Early Career Presentation

Substantial differences in the genetic architecture between artistic and general creativity and their genetic associations with other phenotypes

Penghao Xia^1,2,3, Laura W. Wesseldijk^1,2,4, Yi Lu³, Fredrik Ullén^1,2, Miriam A. Mosing^1,2,3,5

¹Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany. ²Department of Neuroscience, Karolinska Institute, Stockholm, Sweden. ³Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden. ⁴Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. ⁵Melbourne School of Psychological Sciences, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Melbourne, Australia

**Early Career Presentation

Epigenome-Wide Association Study of Loneliness in Older Adulthood

Morgan Lynch¹, Molly Gonnene¹, Matthew Pilgrim¹, Christopher Beam^1,2
1Department of Psychology, University of Southern California, Los Angeles, CA, USA. 2School of Gerontology, University of Southern California, Los Angeles, CA, USA

**Early Career Presentation

Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants

David M. van den Berg¹, Daniel S. Malawsky², Wei Huang², Petr Danecek², Klaudia Walter², Ewan Birney³, Karin J. H. Verweij¹, Dirk J. A. Smit¹, Sarah J. Lindsay², Metthew Hurles², Abdel Abdellaoui¹, Hilary C. Martin²

¹Department of Psychiatry, Amsterdam UMC, Amsterdam, Netherlands. ²Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom. ³European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, United Kingdom

**Early Career Presentation

Bipolar Disorder and Education: Deciphering a Complex Relationship using Genetic and Sibling Differences

Vaishnavi K Madhavan^1,2, Perline Demange³, Ziada Ayorech³, Jouke Jan Hottenga^1,2,4, Meike Bartels^1,2, Eivind Ystrøm³, Michel Nivard^5,6, Wonuola A Akingbuwa^1,2

¹Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam University Medical Centre, Amsterdam, Netherlands. ³PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. ⁴Neurological Disorder Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar. ⁵Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom. ⁶Population Health Sciences, University of Bristol, Bristol, United Kingdom

**Early Career Presentation

Associations of Physical Activity and Genetic Liability With Mental Health Problems in Adolescents

Lu Yang¹, Yeliz Eski², Ilja M. Nolte², Harold Snieder², Eva Corpeleijn², Esther Hartman¹, Catharina A. Hartman³

¹Department of Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, Netherlands. ²Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands. ³Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

**Early Career Presentation

 

Tea Break (30 minutes)

10:30 - 11:00 Thursday, 25th June, 2026
Location: E2 + Foyer

 

Full Symposium 13 
Expanding the Biological Lens: Multi-Omics and the Future of Behavioral Genetics

11:00 - 12:15 Thursday, 25th June, 2026
Location: Uva 1-2 
Chair: Natalia Azcona Granada
Discussant: Anne Geijsen

The Hidden Biology of Wellbeing: A Multi-Omics Analysis Across Genomic, Epigenomic, and Transcriptomic Layers.

Natalia Azcona Granada¹, Anne Geijsen¹, Jenny van Dongen¹, René Pool¹, Floris Huider¹, Pau Badia-i-Mompel², Dirk Pelt¹, Meike Bartels¹

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Heidelberg University, Heidelberg, Germany

**Early Career Presentation

143 Leveraging pQTL and single-cell eQTL data in the brain to interpret GWAS signals for major psychiatric disorders

Laurence Nisbet, Xueyi Shen, Andrew McIntosh

University of Edinburgh, Edinburgh, United Kingdom

**Early Career Presentation

146 Multi-omics of stressful life events

Elissar Azzi¹, Aino Heikkinen¹, Gabin Drouard¹, Teemu Palviainen¹, Colette Kabrita², Jaakko Kaprio¹, Miina Ollikainen^1,3

¹Institute for Molecular Medicine Finland, Helsinki, Finland. ²Notre Dame University, Beirut, Lebanon. ³Minerva Foundation Institute for Medical Research, Helsinki, Finland

**Early Career Presentation

Disentangling the Epigenetic Landscape of Saliva: A Genetically Informed Longitudinal Twin Study of DNA Methylation

Alicia Marie Schowe^1,2, Jana Instinske³, Charlotte K.L. Pahnke⁴, Andreas J. Forstner^4,5, Markus Noethen⁴, Christian Kandler³, Darina Czamara¹, Elisabeth B. Binder¹

¹Max Planck Institute of Psychiatry, Munich, Germany. ²Graduate School of Systemic Neuroscience, Ludwig-Maximilians Universität, Munich, Germany. ³Bielefeld University, Bielefeld, Germany. ⁴Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany. ⁵Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Juelich, Germany

 

Full Symposium 14
Eating Disorders and the Intersection with other Psychopathology: A Genomic Perspective

11:00 - 12:15 Thursday, 25th June, 2026
Location: Uva 3-4 
Chair: Nadia Micali
Discussant: James Li

Effect of internalizing‑disorder and anorexia nervosa genetics on anorexia nervosa risk in a Danish cohort

Stefana Aicoboaie^1,2, Joeri Meijsen^1,2, Morteza Vaez², Dorte Helenius Mikkelsen², Liselotte Vogdrup Petersen³, Cynthia Bulik^4,5,6, Zeynep Yilmaz^3,7,6,8, Nadia Micali^1,2,9

¹Center for Eating and feeding Disorders Research, Mental Health Center Ballerup, Copenhagen University Hospital - Herlev and Gentofte, Ballerup, Denmark. ²Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Copenhagen University Hospital - Amager & Hvidovre Hospital, Roskilde, Denmark. ³The National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark. ⁴Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ⁵Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ⁶Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. ⁷Department of Biomedicine, Aarhus University, Aarhus, Denmark. ⁸Department of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ⁹UCL Great Ormond Street Institute of Child Health, London, United Kingdom

Shared genetic and environmental influences between avoidant/restrictive food intake disorder (ARFID) and neurodevelopmental conditions: a twin study

Baiyu Qi¹, Ruyue Zhang², Liv Hog², Paul Lichtenstein², Sebastian Lundström³, Henrik Larsson^2,4, Cynthia Bulik^2,5,6, Ralf Kuja-Halkola², Mark Taylor², Lisa Dinkler²

¹Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, USA. ²Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. ³Gillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. ⁴School of Medical Sciences, Örebro University, Örebro, Sweden. ⁵Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, USA. ⁶Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, USA

What Anthropometric Genomics Reveals About the Structure of Internalizing and Eating Psychopathology

Katherine Schaumberg¹, Qinwen Zheng², Stefana Aicoboaie³, Agatha A. Laboe¹, Nisha Gottfredson², Quanfa He⁴, James J. Li⁵, Cynthia M. Bulik^2,6, Nadia Micali^3,7, Jin Szatkiewicz²

¹Univeristy of Texas at Austin, Austin, USA. ²University of North Carolina, Chapel Hill, USA. ³Copenhagen University Hospital, Copenhagen, Denmark. ⁴Southern Methodist University, Dallas, USA. ⁵University of Wisconsin, Madison, USA. ⁶Karolinska Institutet, Stockholm, Sweden. ⁷University College London, London, United Kingdom

Tracking depression, eating disorder and sleep disturbance symptoms from adolescence to young adulthood: A cross-lagged twin study

Emerie Sheridan¹, Olakunle Oginni^2,3, Oliver Pain¹, Cathryn Lewis¹, Moritz Herle¹

¹King's College London, London, United Kingdom. ²Cardiff University, Cardiff, United Kingdom. ³Child and Adolescent Mental Health Service, Cardiff and Vale Health Board, Cardiff, United Kingdom

**Early Career Presentation

 

Full Symposium 15
Conceptualizing Internalising Phenotypes for Genetic Research

11:00 - 12:15 Thursday, 25th June, 2026
Location: Erasmus 1 
Chair: Elham Assary
Discussant: Dorret Boomsma

Examining Cross-Ancestry and Developmental Translation of Genetic Effects on Internalising Behaviours and Disorders

Elham Assary¹, Johan Zvrskovec¹, Camille Williams², Justin Tubbs³, Megan Skelton¹, Travis Mallard³, Brittany Mitchell⁴, Maia Choi⁵, Sandra Meier⁶, Nora Strom⁷, Manuel Mattheisen⁶, Gerome Breen¹, Danielle Dick⁵, Thalia Eley¹, Jonathan Coleman¹

¹King's College London, London, United Kingdom. ²Ecole Normale Superieure,, Paris, France. ³Harvard Medical School, Boston, USA. ⁴QIMR Berghofer, Brisbane, Australia. ⁵Rutgers University, New Jersey, United Kingdom. ⁶Dalhousie University, Nova Scotia, Canada. ⁷Humboldt-Universität zu Berlin, Berlin, Germany

**Community, Accessibility, & Growth Presentation

Sex differences in the genetics of anxiety and depression

Jihua Hu^1,2, Katrina Grasby^1,2,3, Brittany Mitchell^1,2,3

¹QIMR Berghofer Medical Research Institute, Brisbane, Australia. ²The University of Queensland, Brisbane, Australia. ³Queensland University of Technology, Brisbane, Australia

**Early Career Presentation

Uncovering the genetic overlap between the Patient Health Questionnaire-9 (PHQ-9), Patient Health Questionnaire-2 (PHQ-2) and Major Depressive Disorder (MDD)

Sam Bentwood, Mark J. Adams, Andrew M. McIntosh, Alex S. F. Kwong

Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom

**Early Career Presentation

Comparison of electronic health record and self-reported measures of depression in the Twins Early Development Study (TEDS)

Celestine Lockhart¹, Megan Skelton¹, Thalia Eley^1,2

¹King's College London, London, United Kingdom. ²UK National Institute for Health Research (NIHR) Biomedical Research Centre, South London and Maudsley Hospital, London, United Kingdom

**Early Career Presentation

 

Full Symposium 16
Progress and Prospects in Autism Genetics

11:00 - 12:15 Thursday, 25th June, 2026
Location: Erasmus 2 
Chair: Melanie de Wit
Discussant: Lukas Schaffer

Potential axes of heterogeneity in autism

Qianshu Ma, Xinhe Zhang, Abigail Alhadeff, Lucas Perry, Simon Baron-Cohen, Varun Warrier

Department of Psychiatry; University of Cambridge, Cambridge, United Kingdom

Polygenic Contributions to Age at Diagnosis Heterogeneity in Autism

Melanie M. de Wit¹, Sander Begeer¹, Varun Warrier^2,3,4, Jakob Grove^5,6,7, Abdel Abdellaoui⁸, Angelica Ronald⁹, Tinca J.C. Polderman^10,1

¹Department of Clinical, Neuro-, and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom. ³Autism Research Centre, Department of Psychiatry, Cambridge, United Kingdom. ⁴Department of Psychology, Cambridge, United Kingdom. ⁵Department of Biomedicine, Aarhus University, Aarhus, Denmark. ⁶Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark. ⁷Center for Genomics and Personalized Medicine, Aarhus, Denmark. ⁸Department of Psychiatry, Amsterdam UMC, location AMC, Amsterdam, Netherlands. ⁹School of Psychology, University of Surrey, Guildford, United Kingdom. ¹⁰Department of Child and Adolescent Psychiatry and Psychosocial Care, Amsterdam UMC, location AMC, Amsterdam, Netherlands

**Early Career Presentation

Unravelling sex chromosome effects in autism genetics

Shannon D'Urso¹, Doug Speed², Jakob Grove³, Kasper Munch¹

¹Bioinformatic Research Center, Aarhus University, Aarhus, Denmark. ²Center for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark. ³Department of Biomedicine, Aarhus University, Aarhus, Denmark

The Next Generation Autism GWAS

Jakob Grove, On behalf of the Psychiatric Genomics Consortium, Broad Institute, and iPSYCH collaboration

Aarhus University, Aarhus, Denmark

 

Lunch / Community, Accessibility, and Growth (CAG) Committee Lunch

12:15 - 13:15 Thursday, 25th June, 2026
Location: EAST & Upper EAST

 

Research Talks 5
Neurodevelopmental Disorders

13:15 - 14:30 Thursday, 25th June, 2026
Location: Uva 1-2
Chair: TBA

Genome-wide association study of infant fussiness and crying in European and multi-ancestry cohorts

Angelica Ronald¹, Anja Hollowell², Anna Gui³, Morgan Morgan¹, Emilie Wigdor⁴, Harriet Cullen⁵, Tomoki Arichi⁵, Frank Dudbridge⁶, Elizabeth Corfield⁷, Laurie Hannigan⁷, Sian Wilson⁸, Catharina Hartman⁹, Mark Johnson¹⁰, Stephan Sanders⁴, Alexandra Havdahl⁷

¹University of Surrey, Guildford, United Kingdom. ²UCL, London, United Kingdom. ³University of Rome Tor Vergata, Rome, Italy. ⁴University of Oxford, Oxford, United Kingdom. ⁵King's College London, London, United Kingdom. ⁶University of Leicester, Leicester, United Kingdom. ⁷University of Oslo, Oslo, Norway. ⁸Harvard Medical School, Boston, USA. ⁹University of Groningen, Groningen, Netherlands. ¹⁰University of Cambridge, Cambridge, United Kingdom 

Partnering with autism community members to co-create genetics education resources

Susan Kuo^1,2, Celia van der Merwe^1,2, Yvonne Blanco², Benjamin Cooley², Dennis Jen², Audrey Thurm³, Stephan Sanders^4,5, Somer Bishop⁵, Elise Robinson^1,2

¹Massachusetts General Hospital, Harvard Medical School, Boston, USA. ²Broad Institute of MIT and Harvard, Cambridge, USA. ³Boston Children's Hospital, Harvard Medical School, Boston, USA. ⁴Oxford University, Oxford, United Kingdom. ⁵University of California San Francisco, San Francisco, USA

**Community, Accessibility, & Growth Presentation
**Public Science Presentation

Clinical and genetic correlates of loss of skills during early development in the Norwegian mother, father and child cohort study (MoBa)

Laura Hegemann¹, Martin Scheiene^1,2, Knut Jørgen Bjuland^1,2, Stian Valand^1,2, Laurie Hannigan^1,2,3, Helga Ask^1,4, Somer Bishop⁵, Alexandra Havdahl^1,2,4

¹PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ²Research Department, Lovisenberg Diakonale Hospital, Oslo, Norway. ³MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom. ⁴PROMENTA Research Center, Department of Psychology, Oslo, Norway. ⁵Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, USA

Reconsidering Sex Differences in Autism Genetics: The Role of Age at Diagnosis

Abigail Alhadeff¹, Lucas Perry¹, Qianshu Ma¹, Xinhe Zhang^1,2, Yuanjun Gu^1,2, Simon Baron-Cohen^1,2,3, Jakob Grove^4,5,6,7,8, Anders D. Børglum^4,5,6,8, Varun Warrier^1,2,3

¹Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom. ²Autism Research Centre, University of Cambridge, Cambridge, United Kingdom. ³Department of Psychology, University of Cambridge, Cambridge, United Kingdom. ⁴iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark. ⁵Center for Genomics and Personalized Medicine (CGPM), Aarhus University, Aarhus, Denmark. ⁶Department of Biomedicine (Human Genetics), Aarhus University, Aarhus, Denmark. ⁷Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark. ⁸Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

Within family Mendelian randomization analysis suggests a reduced effect of liability to Attention Deficit Hyperactivity Disorder on smoking initiation and other health related outcomes

Daisy Crick^1,2,3, Neil Davies^1,4, Sarah Medland⁵, David Evans^2,3,6

¹University College London, London, United Kingdom. ²University of Queensland, Brisbane, Australia. ³University of Bristol, Bristol, United Kingdom. ⁴Norwegian University of Science and Technology, Trondheim, Norway. ⁵QIMR Berghofer Medical Research Institute, Bristol, Australia. ⁶Frazer institute, Brisbane, Australia

**Public Science Presentation

Genetic and phenotypic heterogeneity in ADHD diagnosed in adults over 20 years

Kelli Lehto¹, Triinu Varvas¹, Triinu Ojalo^1,2, Katri Pärna¹, Kadri Kõiv¹

¹Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. ²Psychiatric Clinic, Tallinn Children's Hospital, Tallinn, Estonia

 

Research Talks 6
Methods in Polygenic Scores

13:15 - 14:30 Thursday, 25th June, 2026
Location: Uva 3-4
Chair: TBA

GenoPred: A Comprehensive Pipeline for Standardized, Equitable, and Robust Polygenic Prediction in Behavioural Genetics

Oliver Pain

King's College London, London, United Kingdom

**Community, Accessibility, & Growth Presentation

HAPR: Enhancing the study of polygenic scores with Heritability-Adjusted Prediction

Gareth Markel¹, Jonathan Beauchamp¹, Eduardo Azevedo², Richard Karlsson Linnér³

¹George Mason University, Fairfax, USA. ²Wharton School of the University of Pennsylvania, Philadelphia, USA. ³Universiteit Leiden, Leiden, Netherlands

Estimating gene-environment interactions using polygenic scores across mental health, physical health and educational outcomes

Meredith Han, Jean-Baptiste Pingault

Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom

**Early Career Presentation

Combining Advances in Polygenic Scoring

Kaito Kawakami, Robert Plomin

1Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom

**Early Career Presentation

Developmental polygenic contributions to emotional and behavioural symptom progression

Andrea G. Allegrini^1,2, Jean-Baptiste Pingault^1,2

¹Division of Psychology and Language Sciences, Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom. ²Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom

Improving the predictability and interpretation of polygenic scores for Big Five personality traits

Lisette Tagel¹, Uku Vainik^1,2, Estonian Biobank Research Team², René Mõttus^1,3

¹Institute of Psychology, University of Tartu, Tartu, Estonia. ²Institute of Genomics, University of Tartu, Tartu, Estonia. ³Department of Psychology, Edinburgh University, Edinburgh, United Kingdom

**Early Career Presentation

 

 
Research Talks 7
Gene-Environment Correlation (rGE)

13:15 - 14:30 Thursday, 25th June, 2026
Location: Erasmus 1
Chair: TBA

Victimization, Self-Control & Potential Implications for Psychological and Physical Health

Ana Carolina A. Stoffel¹, Brian B. Boutwell^1,2, Yayouk E. Willems³, Jenny van Dongen^4,5, Catrien C.J.H. Bijleveld^6,7,8,9, Dorret I. Boomsma^10,5, Bodine M.A. Gonggrijp^6,4

¹Department of Criminal Justice & Legal Studies, The University of Mississippi, Mississippi, USA. ²University of Mississippi Medical Center, Jackson, USA. ³Max Planck Research Group Biosocial – Biology, Social Disparities, and Development, Max Planck Institute for Human Development, Berlin, Germany. ⁴Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁵Amsterdam Public Health Research Institute, VU University, Amsterdam, Netherlands. ⁶Netherlands Institute for the Study of Crime and Law Enforcement (NSCR), Amsterdam, Netherlands. ⁷Department of Criminal Law and Criminology, VU University Amsterdam, Amsterdam, Netherlands. ⁸School of Law and Social Justice, University of Liverpool, Liverpool, United Kingdom. ⁹Faculty of law, Anton de Kom University, Paramaribo, Suriname. ¹⁰Department of Complex Trait Genetics, Centre for Neurogenomics and Cognitive Research, VU University, Amsterdam, Netherlands

Estimating direct and indirect genetic effects on emerging variation in depressive symptoms in adolescence: a trio PGS analysis in the MoBa cohort

Meseret Bazezew^1,2,3, Jean-Baptiste Pingault⁴, Bernt Glaser^2,3, Laura Hegemann², Neil Davies^5,6,7, Helga Ask^2,8, Robyn Wootton^1,2,9,10, Adrian Askelund^1,2, Alexandra Havdahl^1,2,3, Laurie Hannigan^1,2,11

¹Research Department, Lovisenberg Diaconal Hospital, Oslo, Norway. ²PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ³Department of Psychology, University of Oslo, Oslo, Norway. ⁴Division of Psychology and Language sciences, University College, London, United Kingdom. ⁵Division of Psychiatry, University College London, London, United Kingdom. ⁶Department of Statistical Science, University College London, London, United Kingdom. ⁷Department of Public Health and Nursing, Norwegian University of Science and Technology, Oslo, Norway. ⁸Department of child health and development, Norwegian Institute of Public Health, Oslo, Norway. ⁹School of Psychological Science, University of Bristol., Bristol, United Kingdom. ¹⁰MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ¹¹Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

**Early Career Presentation

Genetic and Environmental Influences on Depressive Symptoms and Suicidal Ideation among In-School Adolescents in Nigeria

Kehinde Ayodele¹, Opara Onyedikachi², Helena Zavos³, Olakunle Oginni⁴

¹Department of Psychology, Obafemi Awolowo University, Ile-Ife, Nigeria. ²Department of Mental Health, Obafemi Awolowo University, Ile-Ife, Nigeria. ³Department of Psychology, Psychology and Neuroscience, King's college, London, United Kingdom. ⁴Wolfson Centre for Young People's Mental Health, Division of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, United Kingdom

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

Symptom-level genetic analyses of depression in over 1 million individuals

Tingyan Yang¹, Zachary Gerring², Phoebe Imms¹, Eske Derks¹, Jackson Thorp¹

¹QIMR Berghofer, Brisbane, Australia. ²Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia

A landscape of parenting and family effects on offspring development: tests of the rearing environment on psychological and social outcomes from adolescence to middle age.

Scott Vrieze, Victoria Zhu, Tobias Edwards, Kathryn O'Donnell, Brooke Huizenga, Emily Willoughby, James Lee, Sylia Wilson, Steven Malone, Gretchen Saunders, Monica Luciana, William Iacono, Robert Krueger, Glenn Roisman, Matt McGue

University of Minnesota, Minneapolis, USA

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

Gene–environment correlation in childhood maltreatment and its covariation with mental disorders

Jacob Bergstedt¹, Hilda B. Daníelsdóttir¹, Ralf Kuja-Halkola¹, Miriam A. Mosing^1,2, Arvid Sjölander¹, Joëlle A. Pasman³, Donghao Lu¹, Kelli Lehto⁴, Patrick F. Sullivan⁵, Yi Lu¹, Patrik K. E. Magnusson¹, Paul Lichtenstein¹, Ole A. Andreassen^6,7, Fang Fang¹, Unnur A. Valdimarsdóttir^8,1,9

¹Karolinska Institutet, Stockholm, Sweden. ²Max Plank Institute for Empirical Aesthethics, Frankfurt am Main, Germany. ³Amsterdam UMC, Amsterdam, Netherlands. ⁴University of Tartu, Tartu, Estonia. ⁵University of North Carolina at Chapel Hill, Chapel Hill, USA. ⁶University of Oslo, Oslo, Norway. ⁷Oslo University Hospital, Oslo, Norway. ⁸University of Iceland, Reykjavík, Iceland. ⁹Harvard University, Boston, USA

 

Research Talks 8
Eating Disorders, Bipolar Disorder, and Depression

13:15 - 14:30 Thursday, 25th June, 2026
Location: Erasmus 2
Chair: TBA

Associations between polygenic scores for neurodevelopmental and psychiatric disorders with hypomanic symptoms in young people

Georgina Hosang¹, Agnieszka Musial¹, Wangjingyi Liao¹, Mark Taylor², Angelica Ronald³, Margherita Malanchini^1,4

¹Queen Mary University of London, London, United Kingdom. ²Karolinska Institutet, Stockholm, Sweden. ³University of Surrey, Guilford, United Kingdom. ⁴King's College London, London, United Kingdom

Higher quality parent-child relationships predict lower-risk adolescent sexual behavior: A genetically informed sibling comparison

Ryan Dobson^1,2, Tobias Edwards², Alexandros Giannelis², Geoffrey Miller¹, Magdalena March², Emily Willoughby², Robert Krueger², Glenn Roisman², Matt McGue²

¹University of New Mexico, Albuquerque, USA. ²University of Minnesota, Minneapolis, USA

**Early Career Presentation

Genetic and environmental influences on networks of depression, anxiety, and posttraumatic stress symptoms

Jacob Knyspel, Chloe Wong, Jonathan Coleman

King's College London, London, United Kingdom

Exploring age, subtype and symptom specific associations between body size and features of bipolar disorder using summary–level Mendelian randomisation

Alex Monson¹, Grace Power^2,3,4, Maddie Jones¹, Ruby Pallon¹, Jorien L Treur⁵, Gemma M J Taylor³, Claire M A Haworth¹, Robyn E Wootton^1,3,6,7

¹School of Psychological Science, University of Bristol, Bristol, United Kingdom. ²MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom. ³Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ⁴Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia. ⁵Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. ⁶PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ⁷Research Department, Lovisenberg Hospital, Oslo, Norway

**Early Career Presentation

Genetic architecture of eating disorder risk and symptoms in adult population-based Estonian Biobank

Katri Pärna¹, Tuuli Sedman², Hanna Maria Kariis¹, Kristi Krebs¹, Uku Vainik^1,3, Triin Laisk¹, Reedik Mägi¹, Kadri Kõiv¹, Kelli Lehto¹

¹Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. ²Viljandi Hospital Psychiatry Clinic, Viljandi, Estonia. ³Institute of Psychology, University of Tartu, Tartu, Estonia

Genome-wide association meta-analysis of identical depression phenotyping in 404,540 individuals

Rujia Wang^1,2, Floris Huider^3,4,5, Giuseppe Merola¹, Johan Zvrskovec^1,2, Ivan Andrushevich Petukhov^1,2, Madhurbain Singh^1,6, Jodi T. Thomas^7,8, Alex S.F. Kwong^9,10, Mark Adams⁹, Jolien Rietkerk^11,6,12, Justin D. Tubbs, et al.,^13,14,15,16, Roseann E. Peterson^6,17,12, Brittany L. Mitchell^7,8,18, Dorret I. Boomsma^5,4, Gerome Breen^1,2

¹Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom. ²National Institute for Health and Care Research Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom. ³Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁴Amsterdam Public Health Research Institute, Amsterdam, Netherlands. ⁵Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁶Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, USA. ⁷Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia. ⁸School of Biomedical Sciences, The University of Queensland, Brisbane, Australia. ⁹Centre for Clinical Brain Sciences, Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom. ¹⁰Bristol Medical School, University of Bristol, Bristol, United Kingdom. ¹¹Department of Psychiatry, University Medical Centre Groningen, Groningen, Netherlands. ¹²Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, USA. ¹³Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, USA. ¹⁴Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, USA. ¹⁵Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, USA. ¹⁶Department of Psychiatry, Harvard Medical School, Boston, USA. ¹⁷Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, USA. ¹⁸School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia

 

 
Brief Break (15 minutes)

14:30 - 14:45 Thursday, 25th June, 2026
Location: E2 + Foyer

 

Lightning Talks 1
Methods for Family-Based Studies

14:45 - 16:00 Thursday, 25th June, 2026
Location: Uva 1-2

Genome-Wide Scan for Transmission Ratio Distortion Across 43,829 Genotyped Trios From The Norwegian Mother, Father and Child Cohort Study (MoBa) Rules Out Moderate Levels of Distortion at Common Variants but Prioritises Meiosis Related Genes For Follow Up

Shannon D'Urso^1,2, Elizabeth Corfield^3,4,5,6, Laurie Hannigan^7,3,6, Ole Andreassen⁸, Astanand Jugessur^9,10, Kasper Munch², George Davey Smith¹¹, Gibran Hemani^11,6, Liang-Dar Hwang¹, Gunn-Helen Moen^1,12,13,14, Alexandra Havdahl^15,16,3, David Evans^17,12,15

¹Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia. ²Bioinformatic Research Center, Aarhus University, Aarhus, Denmark. ³PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ⁴Psychiatric Genetic Epidemiology Group, Research Department & Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway. ⁵MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ⁶Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom. ⁷Psychiatric Genetic Epidemiology (PaGE) group, Lovisenberg Diaconal Hospital, Oslo, Norway. ⁸Center for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. ⁹Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. ¹⁰Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. ¹¹MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom. ¹²Frazer Institute, The University of Queensland, Brisbane, Australia. ¹³Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. ¹⁴Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. ¹⁵MRC (Medical Research Council) Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom. ¹⁶Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway. ¹⁷Institute for Molecular Bioscience, The University of Queensland, Brisb, Australia

Examining Associations between Monitoring-related Parenting Phenotypes and Youth Externalizing using a novel model: Discordant Sibling Latent Curve Model with Structured Residuals

Kristine Marceau¹, Yongseok Lee¹, Amy Loviska¹, Olivia Robertson², Robert Duncan³

¹Purdue University, West Lafayette, USA. ²Baylor College of Medicine, Houston, USA. ³Colorado State, Fort Collins, USA

Within-family and between-family contributions to polygenic score explanation and prediction

Yujing Lin¹, Francesca Procopio¹, Engin Keser^1,2, Kaito Kawakami¹, Thalia C. Eley¹, Kaili Rimfeld³, Margherita Malanchini², Robert Plomin¹

¹King's College London, London, United Kingdom. ²Queen Mary University of London, London, United Kingdom. ³Royal Holloway University of London, London, United Kingdom

**Early Career Presentation

Assortative mating can mask non-additive genetic contribution to individual differences

Giacomo Bignardi^1,2,3, Hans Fredrik Sunde⁴, Susanne Bruins^5,6, Jared V. Balbona⁷, Simon E. Fisher^1,8, Dorret I. Boomsma^6,9,10

¹Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ²Max Planck School of Cognition, Leipzig, Germany. ³Department of Cognitive Neuropsychology, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany. ⁴Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. ⁵Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁶Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, Netherlands. ⁷Department of Psychiatry, Washington University School of Medicine in St. Louis, Washington, USA. ⁸Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands. ⁹Complex Trait Genetics, Center of Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ¹⁰Amsterdam Reproduction & Development, Research Institute, Amsterdam, Netherlands

**Early Career Presentation

New Questions for Designs as Old as Time: A Multilevel Random Intercepts Approach

Michael Hunter

Pennsylvania State University, University Park, USA

A computationally efficient alternative to longitudinal modeling recovers putative plasticity loci in anthropometric and cognitive traits

Ralph Porneso¹, Alexandra Havdahl^1,2,3, Espen Eilertsen¹, Eivind Ystrom^1,2

¹ PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. ² PyschGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. 3 Research Department, Lovisenberg Diaconal Hospital, Oslo, Norway

Separating Genetic and Social Pathways Using Genomic Data in Families

Abdel Abdellaoui

Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands

 

Lightning Talks 2
Education and Cognition

14:45 - 16:00 Thursday, 25th June, 2026
Location: Uva 3-4
Chair: TBA

The protective effect of education on mental health is driven by cognition

Stephanie Sheir¹, Margherita Malanchini², Liza Darrous³, Zoltan Kutalik⁴, Neil Davies¹, Jean-Baptiste Pingault¹

¹University College London, London, United Kingdom. ²Queen Mary University of London, London, United Kingdom. ³University of Geneva, Geneva, Switzerland. ⁴University of Lausanne, Lausanne, Switzerland

Intergenerational Education Persistence: Evidence from Molecular Genetic Data

Rita Dias Pereira¹, Hans van Kippersluis²

¹Nova School of Business and Economics, Lisbon, Portugal. ²Erasmus School of Economics; Tinbergen Institute, Rotterdam, Netherlands

Using DNA to test direct genetic and environmentally-mediated influences on children’s language and literacy development

Selim Sametoğlu¹, Susanne Bruins², Yola Sol², Alexandra Starr², Bruno Sauce², René Pool², Caroline Rowland^1,3

¹Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ²Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ³Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Parental age and risk of Intellectual Disability in offspring: A 47-year nationwide cohort and cousin comparison study of four million children in Sweden

Xinyue Gu¹, Miriam Martini¹, Shengxin Liu^1,2, Paul Lichtenstein¹, Magnus Tideman³, Tatja Hirvikoski¹, Brian D'Onofrio^1,4, Isabell Brikell^1,5,6, Andrea Wister⁷, Einar Tryti⁷, Henrik Larsson^1,8, Zheng Chang¹, Mark Taylor¹, Ralf Kuja‐Halkola¹, Agnieszka Butwicka^1,7,9,10

¹Karolinska Institutet, Stockholm, Sweden. ²University of Edinburgh, Edinburgh, United Kingdom. ³Halmstad University, Halmstad, Sweden. ⁴Indiana University, Bloomington, USA. ⁵University of Bergen, Bergen, Norway. ⁶Aarhus University, Aarhus, Denmark. ⁷Akershus University Hospital, Lørenskog, Norway. ⁸Örebro University, Örebro, Sweden. ⁹University of Oslo, Oslo, Norway. ¹⁰Medical University of Lodz, Lodz, Poland

**Public Science Presentation

Early Cooperation as a Mediator of the Association Between the Educational Attainment Polygenic Index and Educational Outcomes

Chloe Austerberry^1,2, Hannah Taylor¹, Pasco Fearon¹

¹Centre for Child, Adolescent and Family Research, University of Cambridge, Cambridge, United Kingdom. ²Clare Hall, University of Cambridge, Cambridge, United Kingdom

Predicting Life Outcomes from Childhood and Adolescent Measures of Arithmetic and Reading: A Behavior-Genetics Approach

Giulia Borriello¹, Lilia Geel², Mohini Karhadkar², Robin Corley², Sally Wadsworth², Chandra Reynolds², Daniel Gustavson²

¹Kent State University, Kent, USA. ²University of Colorado Boulder, Boulder, USA

Gene-environment effects of air pollution on cognitive performance

Vinh Phan

Erasmus University Rotterdam, Rotterdam, Netherlands

Beyond years of schooling: Shifting genetic influences across educational milestones in two Norwegian cohorts

Eirik Haugland Kvalvik¹, Yunpeng Wang¹, Kristine B. Walhovd¹, Torkild H. Lyngstad², Ole Rogeberg³

¹Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway. ²Department of Sociology and Human Geography, University of Oslo, Oslo, Norway, Oslo, Norway. ³Ragnar Frisch Centre for Economic Research, Oslo, Norway

 

 
Lightning Talks 3
Personality & Beliefs

14:45 - 16:00 Thursday, 25th June, 2026
Location: Erasmus 1
Chair: TBA

Education shapes personality through direct and indirect genetic effects

Kertti Elery Kaljuste¹, René Mõttus^2,1, Uku Vainik^1,3

¹Institute of Psychology, University of Tartu, Tartu, Estonia. ²Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom. ³Institute of Genomics, University of Tartu, Tartu, Estonia

Use of Digital Devices Moderates Genetic Influences on Loneliness Among Older Adults

Deborah Finkel^1,2, Anna Dahl Aslan³

¹University of Southern California, Los Angeles, USA. ²Jönköping University, Jönköping, Sweden. ³University of Skövde, Skövde, Sweden

Positive Affect Under Stress and High Temperamental Effortful Control as Resilience Factors Environmentally-Linked to Child Psychopathology

Kathryn Lemery-Chalfant, Alexys S Murillo, Sierra Clifford, Qingyang Liu, Savannah G Ostner, Isabella S Davis

Arizona State University, Tempe, AZ, USA

---

Intelligence and personality share a genetic and biological basis

Andrew Buonaccorsi, Colin DeYoung, Dylan Maher, Tobias Edwards

University of Minnesota - Twin Cities, Minneapolis, USA

**Early Career Presentation

Genetic and Environmental Contributions to Personality-Stress Exposure Covariance in a Dutch Twin Sample

Felix Reichelt¹, Haixia Gu², Rujia Wang^1,3, Bodine Gongrijp⁴, Catharina A. Hartman², Maryam Kavousi⁵, Harold Snieder¹, Eco JC de Geus⁴

¹Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ²Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ³Social, Genetic, and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology and Neuroscience; King's College London, Denmark Hill, Camberwell, London, United Kingdom. ⁴Department of Biological Psychology, VU University Amsterdam, Amsterdam, Netherlands. ⁵Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands

**Early Career Presentation

**Public Science Presentation

Personality Traits, Human Capital Formation, and Economic Behavior: Exploiting Random Genetic Variation to Study the Causal Effects of Personality Traits

Leandro Carvalho¹, Sjoerd van Alten², Silvia Barcellos³, Dilnoza Muslimova², Stephen Dorn³, Qiongshi Lu³, Catharina Hartman⁴, Titus Galama¹

¹USC, Los Angeles, USA. ²VU Amsterdam, Amsterdam, Netherlands. ³UW-Madison, Madison, USA. ⁴University of Groningen, Groningen, Netherlands

 

Lightning Talks 4
Biomarkers (DNAm & Cortisol)

14:45 - 16:00 Thursday, 25th June, 2026
Location: Erasmus 2 

Chair: TBA

Children's DNA Methylation and Family Dynamics in a Congo Basin Subsistence Community: Links with Health Outcomes

Meingold Hiu-ming Chan¹, Sarah M. Merril², Beryl Zhuang^3,4,5, Julia L. MacIsaac^4,5, Valchy Miegakanda⁶, Sheina Lew-Levy⁷, Adam H. Boyette⁸, Michael S. Kobor^5,4,3, Lee T. Gettler⁹

¹Purdue University, West Lafayette, USA. ²University of Massachusetts Lowell, Lowell, USA. ³University of British Columbia, Vancouver, Canada. ⁴BC Children's Hospital Research Institute, Vancouver, Canada. ⁵Edwin S. H. Leong Centre for Healthy Aging, Vancouver, Canada. ⁶Laboratoire National de Sante Publique, Brazzaville, Congo. ⁷Durham University, Durham, United Kingdom. ⁸Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. ⁹University of Notre Dame, Notre Dame, USA

**Community, Accessibility, & Growth Presentation

Cortisol and Depressive Symptoms across the Transition to Adolescence: Longitudinal Genetic and Environmental Contributions

Savannah G. Ostner, Mary C. Davis, Leah D. Doane, Kathryn Lemery-Chalfant

Arizona State University, Tempe, AZ, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

Salivary epigenetic signatures of poverty and socioeconomic disadvantage in childhood

Abby J. deSteiguer¹, Qiao Wu², Alicia M. Schowe³, Bastian Mönkediek^4,5, Trey Smith⁶, Joshua A. Goode⁶, Elliot M. Tucker-Drob¹, Colter Mitchell⁶, K. Paige Harden¹, Laurel Raffington²

¹University of Texas at Austin, Austin, USA. ²Max Planck Institute for Human Development, Berlin, Germany. ³Max Planck Institute of Psychiatry, Munich, Germany. ⁴Ludwig Maximilian University of Munich, Munich, Germany. ⁵Bielefeld University, Bielefeld, Germany. ⁶University of Michigan, Ann Arbor, USA

**Early Career Presentation

Associations among socioeconomic status and epigenetic aging across the first few years of life

Jessica Sperber Knott¹, Melissa Miller², Ariel Bellatin², Frances Champagne², Kimberly Noble³

¹Max Planck Institute for Human Development, Berlin, Germany. ²University of Texas, Austin, USA. ³Teachers College, Columbia University, New York City, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

Do the offspring methylome and metabolome mediate direct and indirect genetic effects for externalizing behaviors?

Fiona A. Hagenbeek¹, Li Tian², Floris Huider¹, Conor V. Dolan¹, Erik A. Ehli³, Dorret I. Boomsma¹, Christian Kandler⁴, Meike Bartels¹, Jari Lahti², Bastian Mönkediek⁴, René Pool¹, Jenny van Dongen¹

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²University of Helsinki, Helsinki, Finland. ³Avera McKennan Hospital, Sioux Falls, USA. ⁴University of Bielefeld, Bielefeld, Germany

The Physiological Associations of Marriage: An Epigenome-wide Analysis of Marital Status

Molly Gonenne¹, Matthew Pilgrim¹, Morgan Lynch¹, Christopher Beam^1,2

¹Department of Psychology, University of Southern California, Los Angeles, USA. ²Department of Gerontology, University of Southern California, Los Angeles, USA

**Early Career Presentation

The joint genetic structure of molecular and metabolic phenotypes

Christiaan de Leeuw, Marijn Schipper, Nathan Bell

Vrije Universiteit, Amsterdam, Netherlands

Plasma biomarkers predict conversion to amyloid-β positivity and cognitive decline in cognitively unimpaired individuals

Rebecca Rousset¹, Eva Drop¹, Eco de Geus², Inge Verberk¹, David Wilson³, Lynn Boonkamp¹, Jori Tomassen¹, Sophie van der Landen¹, Frederik Barkhof^1,4, Lyduine Collij⁵, Peter Jelle Visser⁶, Charlotte Teunissen¹, Anouk den Braber^1,2

¹Amsterdam UMC, Amsterdam, Netherlands. ²Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ³Quanterix, Billerica, USA. ⁴UCL Institute of Neurology, London, United Kingdom. ⁵Lund University, Lund, Sweden. ⁶Maastricht University, Maastricht, Netherlands

**Early Career Presentation

 

 
Tea Break (30 minutes)

16:00 - 16:30 Thursday, 25th June, 2026
Location: E2 + Foyer

 

 
Lightning Symposium 1
Genetic and Environmental Sources of Personality and Outcomes: Novel Multi-Rater, Longitudinal, Twin, and Genomic Insights

16:30 - 17:30 Thursday, 25th June, 2026
Location: Uva 1-2
Chair: Jana Instinske
Discussant: Ted Schwaba

Gene-Environment Correlation Underlying Neuroticism and Extraversion

Christoher Beam¹, Ebrahim Zandi¹, Deborah Finkel^1,2, Eric Turkheimer³, Deborah Davis⁴

¹University of Southern California, Los Angeles, USA. ²Jönköping University, Jönköping, Sweden. ³University of Virginia, Charlottesville, USA. ⁴University of Louisville, Louisville, USA

Are Life Experiences Truly Environmental Factors Driving Personality Differences? A Longitudinal Twin Study

Jana Instinske¹, Steven Wezel², Christian Kandler^1,3

¹Bielefeld University, Bielefeld, Germany. ²University of Basel, Basel, Switzerland. ³Joint Institute for Individualisation in a Changing Environment, Münster and Bielefeld, Germany

**Early Career Presentation

The Genetics of Personality Self-Perception are Biologically Coherent and Related to Positive Life Outcomes

Lindsay S. Ackerman¹, Kerli Ilves², Liisi Ausmees², Uku Vainik^2,3, Rene Mottus^2,4, Ted Schwaba¹

¹Michigan State University, East Lansing, USA. ²University of Tartu, Tartu, Estonia. ³McGill University, Montreal, Canada. ⁴University of Edinburg, Edinburgh, United Kingdom

**Early Career Presentation

Personality Traits and Socio-Political Attitudes: How and Why are they Connected?

Edward Bell¹, Jana Instinske², Christian Kandler^2,3

¹Department of Sociology, University of Western Ontario, London, Canada. ²Department of Psychology, Bielefeld University, Bielefeld, Germany. ³Joint Institute for Individualisation in a Changing Environment (JICE), University of Münster and Bielefeld University, Münster and Bielefeld, Germany

 

Lightning Symposium 2
Are Genetic Influences Temporally Bound?

16:30 - 17:30 Thursday, 25th June, 2026
Location: Uva 3-4
Chair: S. Alexandra Burt
Discussant: Michael Hunter

Temporal Influences on Twin Studies Published from 1958 to 2012: A Re-analysis of Polderman et al. (2015)

S. Alexandra Burt, Logan Gillenwater, Ted Schwaba

Michigan State University, East Lansing, USA

Confirming Temporal Influences on Heritability Estimates with Raw Data obtained from two Large Twin Samples

Logan A. Gillenwater¹, Matt McGue², Ted Schwaba¹, S. Alexandra Burt¹

¹Department of Psychology, Michigan State University, East Lansing, MI, USA. ²Department of Psychology, University of Minnesota, Minneapolis, MN, USA

**Early Career Presentation

Temporal Changes in the Heritability of Longevity over the last 300 years: Preliminary Evidence from Extended Pedigrees with 176 Million Kinship pairs

S. Mason Garrison¹, Michael D. Hunter², Ken R. Smith³, S. Alexandra Burt⁴

¹Department of Psychology, Wake Forest University, Winston-Salem, USA. ²Department of Human Development and Family Studies, Pennsylvania State University, University Park, USA. ³Department of Family & Consumer Studies and Huntsman Cancer Institute, Salt Lake City, USA. ⁴Department of Psychology, Michigan State University, East Lansing, USA

Birth cohort differences in the molecular genetic architecture of complex phenotypes

Ted Schwaba, Logan Gillenwater, S. Alexandra Burt

Michigan State University, East Lansing, USA

 

 
Lightning Symposium 3
Shared Genetic Background Between Hormones, Fertility Traits, and Brain Disorders

16:30 - 17:30 Thursday, 25th June, 2026
Location: Erasmus 1 
Chair: Nikki Hubers
Discussant: Jaakko Leinonen

Genetic contributions to reduced fertility in people with epilepsy

Nikki Hubers^1,2, Peter M. Socha¹, Jakob Christensen^3,4, Julie Werenberg Dreier^1,5, Bjarni J. Vilhjálmsson^1,2,6

¹National Centre for Register-based Research, Aarhus University, Aarhus, Denmark. ²SMARTBiomed Pioneer Centre, Aarhus, Denmark. ³Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. ⁴Department of Neurology, Aarhus University Hospital, Aarhus, Denmark. ⁵Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark. ⁶Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, USA

**Early Career Presentation

Genome-wide association study of oestradiol levels in pre-menopausal women: Modelling the menstrual cycle

Margot van de Weijer¹, Rada Veeneman¹, Janne Pott², Birit Broekman³, Stephen Burgess², Michel Nivard⁴

¹Genetic Epidemiology, Department of Psychiatry, Amsterdam UMC, location University of Amsterdam, Amsterdam, Netherlands. ²MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom. ³Department of Psychiatry, Amsterdam, Netherlands. ⁴Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom

Lifecourse genome-wide association analyses of circulating sex hormones identify age-dependent genetic associations

Grace Power^1,2, Genevieve Leyden¹, David Carslake¹, Lifecourse GWAS Consortium Collaborators¹, George Davey Smith¹, Gibran Hemani¹, Eleanor Sanderson¹

¹MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom. ²Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia

**Community, Accessibility, & Growth Presentation

Shared Genetic Architecture Between Endometriosis and Psychiatric Conditions May Explain Comorbidity

Marika Rostvall^1,2,3, Cecilia Magnusson^1,3, Kristina Gemzell-Danielsson^4,5, Johanna Sieurin^1,3, Anders Børglum^6,7,8, Jakob Grove^6,7,8,9, Mette Nyegaard¹⁰, Anxiety Disorder Working Group of the Psychiatric Genomics Consortium -¹¹, Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium -¹¹, Emma Bränn^12,3, Kyriaki Kosidou^1,3, Jacob Bergstedt¹², Viktor Ahlqvist^12,3,13

¹Department of Global Public Health Karolinska Institutet, Stockholm, Sweden. ²Karolinska University Hospital, Stockholm, Sweden. ³Centre for Epidemiology and Community Medicine, Stockholm, Sweden. ⁴Department of women's and Children's Health Karolinska Institutet, Stockholm, Sweden. ⁵Division for Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden. ⁶Department of Biomedicine, Aarhus University, Aarhus, Denmark. ⁷The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark. ⁸Center for Genomics and Personalized Medicine, Aarhus, Denmark. ⁹Bioinformatics Research Centre, BiRC, Aarhus University, Aarhus, Denmark. ¹⁰Department of Congenital Disorders, Statens Serum Institute, Copenhagen, Denmark. ¹¹https://pgc.unc.edu/, -, Sweden. ¹²Unit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. ¹³Aarhus University, Aarhus, Denmark

 

 
Lightning Symposium 4
Disentangling Direct and Indirect Genetic Effects on Complex Traits: Insights from Two Large-Scale Family Studies

16:30 - 17:30 Thursday, 25th June, 2026
Location: Erasmus 2
Chair: Hanna van Loo
Discussant: Eivind Ystrøm

Intergenerational Transmission via Genetic Nurture: From Substance Use to Misuse

Mannan Luo¹, Victória Trindade Pons¹, Michael Zakharin², Jean-Baptiste Pingault^3,4, Nathan Gillespie^2,5, Hanna van Loo¹

¹University Medical Center Groningen, Groningen, Netherlands. ²Virginia Commonwealth University, Richmond, USA. ³University College London, London, United Kingdom. ⁴King’s College London, London, United Kingdom. ⁵QIMR Berghofer, Brisbane, Australia

**Public Science Presentation

Environment-by-PGS interaction effects in internalizing and functional disorder symptoms in the Lifelines cohort using a sibling design

Martje Bos¹, Michael C. Neale², Nathaniel S. Thomas³, Judith G. M. Rosmalen^1,4, Harold Snieder⁵, Nathan A. Gillespie^2,6, Hanna M. van Loo¹

¹Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ²Virginia Institute for Psychiatric and Behaviour Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA. ³Department of Psychiatry, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA. ⁴Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ⁵Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. ⁶Genetic Epidemiology, QIMR Berghofer, Brisbane, Australia

**Early Career Presentation

Heterogeneity in genetic nurture effects across education, BMI, and psychopathology in the Lifelines cohort

Victória Trindade Pons¹, Mannan Luo¹, Nathan A. Gillespie², Albertine J. Oldehinkel¹, Hanna M. van Loo¹

¹University Medical Center Groningen, Groningen, Netherlands. ²Virginia Commonwealth University, Richmond, USA

**Early Career Presentation

Twin-Family Genetic Nurture SEM: Polygenic Score Estimation of Parental Effects on Complex Traits

Nathan Gillespie¹, Michael Zakharin¹, Mei-Hsin Su¹, Mannan Luo², Victória Trindade Pons², Michael Neale¹, Jared Balbona³, Hanna van Loo²

¹Virginia Commonwealth University, Richmond, USA. ²University Medical Center Groningen, Groningen, Netherlands. ³Virginia Commonwealth University, R, USA

**Public Science Presentation

 

 
Poster Session 2 & Reception

17:30 - 19:00 Thursday, 25th June, 2026
Location: E2 + Foyer

T1. Longitudinal evidence of school environment effects on mental health from genetically sensitive within- and between-family designs

Samuel Berry¹, Kadri Arumäe¹, Rebecca Ferdinand¹, Laurie Hannigan², Margherita Malanchini^3,4, Robert Plomin⁴, Ragnhild Eek Brandlistuen², Kaili Rimfeld¹

¹Royal Holloway University of London, London, United Kingdom. ²Norwegian Institute of Public Health, Oslo, Norway. ³Queen Mary University of London, London, United Kingdom. ⁴King's College London, London, United Kingdom

T2. Shared Genetic Influences Between Cognitive Disengagement Syndrome and Childhood Psychopathology: Evidence from a General Population Twin Study

Stefano De Francesco^1,2, Ludovica Giani^2,3, Alessio Pelucchi², Emanuela Medda⁴, Corrado Fagnani⁴, Simona Scaini^2,3

¹Sigmund Freud PrivatUniversität, Fakultät für Psychologie, Vienna, Austria. ²Child and Youth Lab, Sigmund Freud University, Milan, Italy. ³Italian Psychotherapy Clinics, Child and Adolescent Unit, Studi Cognitivi Group, Milan, Italy. ⁴Centre for Behavioural Sciences and Mental Health, Italian Twin Registry, Istituto Superiore di Sanità, Rome, Italy

T3. HEXACO personality traits and flow: A behavior genetic analysis

Ana Butkovic, Denis Bratko

Faculty of Humanities and Social Sciences, Zagreb, Croatia

T4. Genetically-Informed Derivation of Phenotypic Big Five Scores in the UK BioBank Using a Brute-Force Psychometric Scale Reduction Algorithm

Patrick Maher¹, Yavor Dragostinov^2,3

¹Goldsmiths, University of London, London, United Kingdom. ²University of Texas at Austin, Austin, USA. ³Population Research Center University of Texas at Austin, Austin, USA

**Early Career Presentation

T5. Mapping changes within physical and mental health comorbidity over time using a longitudinal cohort

Aahan Bajpai¹, Rafael Geurgas¹, Evelina Akimova¹, Robbee Wedow^1,2, Katherine Thompson¹

¹Purdue University, West Lafayette, USA. ²Indiana University School of Medicine, West Lafayette, USA

**Early Career Presentation

T6. Longitudinal and Genetically Informed Insights into Mental Health, Wellbeing, and Resilience Across Development

Lianne P. de Vries^1,2, Christel M. Middeldorp^3,4,5,2, Meike Bartels^1,2

¹Department of Biological Psychology, Vrije Universiteit, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam, Netherlands. ³Department of Child and Adolescent Psychiatry and Psychology, Amsterdam UMC, Amsterdam, Netherlands. ⁴Arkin Mental Health Care, Amsterdam, Netherlands. ⁵Levvel, Academic Center for Child and Adolescent Psychiatry, Amsterdam, Netherlands

T7. Genome and environment in action at the local level: Mapping moderated gene-environment interaction across neighborhood-level exposures and wellbeing-related outcomes

David Leitritz¹, René Pool¹, Lannie Ligthart¹, Meike Bartels^1,2, Dirk Pelt^1,2

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health, Amsterdam, Netherlands

**Early Career Presentation

T8. Genetic and Epigenetic Variants of Physical Activity and Sedentary Behaviours: A Systematic Review

Balapuwaduge Isuru Layan Madusanka Mendis^1,2, Lianne de Vries^1,2, Floris Huider^1,2, Eco de Geus^1,2

¹Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit of Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, Netherlands

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

T9. Gene-environment correlations in mental health: Evidence from UK Biobank

Sourena Soheili-Nezhad, Lennart Oblong, Hailey Davis, Pietro Bassani, Emma Sprooten

Medical Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, Nijmegen, Netherlands

T10. Causally-informative analyses on the relationship between traumatic brain injury and dementia: A Finnish twin and population study

Stephanie Zellers¹, Wivi Taalas², Jaakko Kaprio¹, Jari Siironen², Rahul Raj²

¹Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. ²Neurosurgery, Helsinki University Hospital, Helsinki, Finland

T11. Using Genetics to Estimate Intergenerational Effects of Dementia on Work, Income and Wealth

Marina Aguiar Palma¹, Sjoerd van Alten², Silvia Barcellos³, Leandro Carvalho⁴

¹Vrije Universiteit, Amsterdam, Netherlands. ²Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ³University of Wisconsin Madison, Wisconsin, USA. ⁴University of Southern California, Los Angeles, USA

T12. Genetic architecture of Alzheimer’s disease–related plasma biomarkers: Estimating unique and shared genetic effects using a multivariate twin design

Aino Aaltonen¹, Teemu Palviainen¹, Sami Heikkinen², Sanna-Kaisa Herukka^3,2, Mikko Hiltunen², Tarja Kokkola², Sari Kärkkäinen², FinnGen Consortium¹, Aarno Palotie^1,4,5, Heiko Runz¹, Valtteri Julkunen³, Jaakko Kaprio¹, Toni T Saari¹, Eero Vuoksimaa¹

¹University of Helsinki, Helsinki, Finland. ²University of Eastern Finland, Kuopio, Finland. ³Kuopio University Hospital, Kuopio, Finland. ⁴Massachusetts General Hospital, Boston, USA. ⁵The Broad Institute of MIT and Harvard, Cambridge, USA

T13. Pathway polygenic risk scores in relation to longitudinal trajectories of blood biomarkers for Alzheimer’s disease

Martin Nakash¹, Emilija Romic², Karolina Kauppi^1,2, Andrea L Benedet³, Henrik Zetterberg³, Yuling Yu¹, Ida K Karlsson¹

¹Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. ²Department of Medical and Translational Biology, Umeå University, Umeå, Sweden. ³Department of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden

T14. Genetically informed disease staging of amyloid pathology reveals increased functional connectivity predicts future progression of Alzheimer pathology

Senne Lageman^1,2, Anouk den Braber^1,2,3, Luigi Lorenzini⁴, Mara ten Kate⁴, Floor Duits^1,2, Charlotte Teunissen⁵, Frederik Barkhof⁴, Pieter Jelle Visser^1,6,7, Betty Tijms^1,2

¹Alzheimer Center Amsterdam, Amsterdam UMC location VUmc, Amsterdam, Netherlands. ²Amsterdam Neuroscience, Neurodegeneration, Amsterdam, Netherlands. ³Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁴Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands. ⁵Neurochemistry Laboratory, Amsterdam UMC location VUmc, Amsterdam, Netherlands. ⁶Alzheimer Center Limburg, Maastricht, Netherlands. ⁷Department of Neurobiology, Karolinska Institutet, Stockholm, Sweden

T15. Epigenetic ageing and plasma biomarkers of Alzheimer’s disease pathology and neurodegeneration in the Netherlands Twin Register

Jenny van Dongen^1,2, Lotte Schoen¹, Rebecca Z. Rousset^3,4, Lannie Ligthart^1,2, Charlotte E. Teunissen^3,4, Eco J. C. de Geus^1,2, Anouk den Braber^1,5,4

¹Vrije Universiteit Amsterdam, Department of Biological Psychology, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam, Netherlands. ³Department of Clinical Chemistry, Amsterdam UMC, Amsterdam, Netherlands. ⁴Amsterdam Neuroscience, Neurodegeneration, Amsterdam, Netherlands. ⁵Alzheimer Center Amsterdam, Neurology, Amsterdam UMC, Amsterdam, Netherlands

T16. APOE ε4 carriership status enhances age-related changes in Alzheimer’s disease plasma biomarkers concentrations

Rebecca Rousset¹, Anouk den Braber^1,2, Bram Bongers¹, Lynn Boonkamp¹, David Wilson³, Lannie Ligthart², René Pool², Pieter Jelle Visser⁴, Sophie van der Lander¹, Eco de Geus², Charlotte Teunissen¹

¹Amsterdam UMC, Amsterdam, Netherlands. ²Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ³Quanterix, Billerica, USA. ⁴Maastricht University, Maastricht, Netherlands

**Early Career Presentation

T17. The Genetic Architecture of Psychopathological, Neurodegenerative, and Somatic Symptoms in Older Adults: A Twin Study

Eleni Diamantopoulou¹, Conor Dolan^2,1, Dorret Boomsma^2,3

¹Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health (APH) research institute, Amsterdam, Netherlands. ³Center for Neurogenomics and Cognitive Research, Amsterdam, Netherlands

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

T18. Environmental Influences and Gene–Environment Interplay in Cognitive Aging: Access to Parks and Trails

Ashley Barrows^1,2, Jessica Finlay^3,4, Elizabeth Muñoz⁵, Harry Smolker⁶, Ryan Bruellman⁷, Naomi Friedman^1,2, Daniel Gustavson^1,2, Robin Corley¹, Sally Wadsworth¹, Soo Rhee^1,2, Matthew Keller^1,2, Chandra Reynolds^8,9,1,2

¹Institute for Behavioral Genetics, University of Colorado, Boulder, USA. ²Department of Psychology and Neuroscience, University of Colorado, Boulder, USA. ³Institute of Behavioral Science, University of Colorado, Boulder, USA. ⁴Department of Geography, University of Colorado, Boulder, USA. ⁵Human Development and Family Sciences, The University of Texas, Austin, USA. ⁶Institute of Cognitive Science, University of Colorado, Boulder, USA. ⁷Genetics, Genomics, and Bioinformatics, University of California Riverside, Riverside, USA. ⁸University of California, Riverside, Riverside, USA. ⁹Department of Psychology, Riverside, Riverside, USA

**Early Career Presentation

T19. Intraindividual Variability as a Marker of Cognitive Aging: Genetic and Modifiable Risk Factors in CATSLife2 cohorts

Claudia Paniagua-Ugarte¹, Anqing Zheng¹, Tara Henechowicz¹, Naomi Friedman¹, Daniel Gustavson¹, Kaili Rimfield², Matthew Keller¹, Robert Plomin³, Chandra Reynolds¹

¹University of Colorado Boulder, Boulder, USA. ²Royal Holloway, University of London, Bloomsbury, United Kingdom. ³Kings College, London, United Kingdom

**Early Career Presentation

T20. Stability of Genetic and Environmental Influences on Executive Function Across Midlife through Old Age

Daniel Gustavson¹, Mohini Karhadkar¹, William Kremen², Carol Franz², Jeremy Elman², Chandra Reynolds¹

¹University of Colorado Boulder, Boulder, USA. ²University of California San Diego, San Diego, USA

T21. The adjusted effect of occupational cognitive demands on age-related cognitive impairment: A genetically informed cohort study

Sam Brouwers¹, Miriam Mosing^1,2, Malin Ericsson¹

¹Karolinska Institutet, Stockholm, Sweden. ²Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany

**Early Career Presentation

T22. Genetic architecture of mathematical abilities: a GWAS meta-analysis  using standardised educational and psychometric measures

Silvia Paracchini¹, Krzysztof Marianski¹, Filippo Abbondanza¹, Alessandro Gialluisi², Else Eising³, Simon Fisher^3,4, Gerd Schulte-Körne⁵, Kristina Moll⁵, GenLang Consortium³

¹University of St Andrews, St Andrews, United Kingdom. ²LUM University, Bari, Italy. ³Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ⁴(4) Donders Institute for Brain, Cognition, and Behaviour, Nijmegen, Netherlands. ⁵Ludwig-Maximilians-University Hospital, Munich, Germany

T23. Analysis of the Flynn Effect at the Subtest Level Across Childhood

Alyssa Kam¹, Evan Giangrande^2,3, Christopher Beam^1,4, Eric Turkheimer⁵, Sophie Bell⁵, Deborah Finkel^6,7, Sarah Deans⁸, Ariel King⁸, Deborah Davis⁹

¹Department of Psychology, University of Southern California, Los Angeles, USA. ²Analytic & Translational Genetics Unit and Psychiatric & Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, USA. ³Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, USA. ⁴Leonard Davis School of Gerontology, University of Southern California, Los Angeles, USA. ⁵Department of Psychology, University of Virginia, Charlottesville, USA. ⁶Center for Economic and Social Research, University of Southern California, Los Angeles, USA. ⁷Institute for Gerontology, Jönköping University, Jönköping, Sweden. ⁸Norton Children’s Research Institute affiliated with the University of Louisville School of Medicine, Louisville, USA. ⁹Department of Pediatrics, University of Louisville School of Medicine, Louisville, USA

**Early Career Presentation

T24. Interaction between genetic predisposition and perinatal factors in the prediction of Special Educational Needs in the Born in Bradford cohort

Emanuele Esposito¹, Camille Williams¹, Sophie Von Stumm², Franck Ramus³

¹ENS-PSL, Paris, France. ²University of York, York, United Kingdom. ³CNRS - ENS, Paris, France

**Community, Accessibility, & Growth Presentation

T25. Project COMPRENDO: Uncovering genetic contributions to language and reading comprehension

Danielle Admiraal¹, Kyla McConnell¹, Hayley S. Mountford², Michelle Luciano², Elsje van Bergen^3,4, Else Eising¹, Simon E. Fisher^1,5

¹Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ²School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, United Kingdom. ³Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ⁴University of Oslo, Oslo, Norway. ⁵Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands

**Early Career Presentation

T26. From Language to Literacy: Longitudinal Genetic Influences Across Development

Megan Maxton, Stephen Petrill

The Ohio State University, Columbus, USA

**Early Career Presentation

T27. Phenotypic and Genetic Correlations for Self-Reported Communication Skills in the Lifelines Cohort

Hope S. Lancaster¹, Simon E. Fisher^2,3, Else Eising²

¹Center for Childhood Deafness Language and Learning, Boys Town National Research Hospital, Omaha, NE, USA. ²Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. ³Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands

T28. Sex-specific contemporary selection on educational attainment–associated genetic variation in Estonia

Ivan A. Kuznetsov¹, Alexandros Gianneli², Cornelius A. Rietveld², Uku Vainik^1,3,4, Vasili Pankratov^1,5

¹Institute of Genomics, University of Tartu, Tartu, Estonia. ²Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, Netherlands. ³Institute of Psychology, University of Tartu, Tartu, Estonia. ⁴Montreal Neurological Institute, McGill University, Montreal, Canada. ⁵Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark

**Early Career Presentation

T29. Internalized achievement pressure and burnout: A genetically informative study

Ana Henriques Fuerst^1,2, Jurgita Narusyte³, Fredrik Ullén^4,2, Pia Svedberg³, Miriam Mosing^1,2

¹Max Planck Institute for Empirical Aesthetics, Department of Cognitive Neuropsychology, Behavior Genetics Unit, Frankfurt, Germany. ²Karolinska Institutet, Department of Neuroscience, Neuropsychology of Music, Stockholm, Sweden. ³Karolinska Institutet, Department of Clinical Neuroscience, Division of Insurance Medicine, Stockholm, Sweden. ⁴Max Planck Institute for Empirical Aesthetics, Department of Cognitive Neuropsychology, Frankfurt, Germany

**Early Career Presentation

T30. Examining the specific predictive utility of spatial ability for STEM success and subject choice

Quan Zhou¹, Ziye Wang¹, Kaili Rimfeld², Andrea G. Allegrini³, Robert Plomin⁴, Margherita Malanchini¹

¹Queen Mary University of London, London, United Kingdom. ²Royal Holloway University of London, London, United Kingdom. ³University College London, London, United Kingdom. ⁴King’s College London, London, United Kingdom

**Early Career Presentation

T31. Distinct genomic and phenotypic associations between inattention and hyperactivity-impulsivity symptom domains and educational attainment in the general adult population

Triinu Varvas¹, Elis Haan¹, Laura Hegemann^2,3, Natàlia Pujol-Gualdo^1,4, Sofiya Babok¹, Katri Pärna¹, Siim Kurvits¹, Kadri Kõiv¹, Melissa Vos⁵, Martje Bos⁶, Catharina Hartman⁵, Helga Ask², Kelli Lehto¹

¹Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. ²PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ³Psychiatric Genetic Epidemiology Group, Research Department, Lovisenberg Diaconal Hospital, Oslo, Norway. ⁴Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain. ⁵University of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, Netherlands. ⁶University of Groningen, University Medical Center Groningen, Department of Epidemiology, Unit of Genetic Epidemiology and Bioinformatics, Groningen, Netherlands

T32. Life-Course Determinants of Educational Attainment: Cognition, Family Background, and Genetic Propensity

Malin Ericsson¹, Miriam Mosing^1,2

¹Karolinska Institutet, Stockholm, Sweden. ²Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany

T33. A large-scale adoption study on the intergenerational mobility of education and income.

Alexandros Giannelis, Tim Wienand, C.A. Rietveld

Erasmus University Rotterdam, Rotterdam, Netherlands

T34. Genetic contributions to brain drain and social inequality in the Netherlands

Lyydia Alajääskö¹, Lannie Ligthart¹, Titus Galama^1,2, Wonu Akingbuwa¹, Abdel Abdellaoui³

¹Vrije Universiteit, Amsterdam, Netherlands. ²University of Southern California, Los Angeles, USA. ³Amsterdam UMC, Amsterdam, Netherlands

T35. Sources of Inequality at Birth: The Interplay Between Genes and Parental Socioeconomic Status

Pietro Biroli¹, Titus Galama^2,3, Nicolau Bassols¹

¹University of Bologna, Bologna, Italy. ²University of Southern California, Los Angeles, USA. ³VU Amsterdam, Amsterdam, Netherlands

T36. Etiologic Links Between Personality Pathology and Workplace Behavior

Tianfang Yang^1,2, Jacob Anderson², Robin Corley³, Christian Hopfer⁴, Matt McGue², Soo Rhee³, Sylia Wilson², Scott Vrieze², Jarrod Ellingson⁴

¹University of Oslo, Oslo, Norway. ²University of Minnesota, Minneapolis, USA. ³University of Colorado Boulder, Boulder, USA. ⁴University of Colorado Anschutz, Denver, USA

**Early Career Presentation

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

T37. Effects of Genetic Propensity for Education on Labor Market and Health Trajectories across the Working Life

Stefano Lombardi^1,2,3, Nurfatima Jandarova⁴, Kristina Zguro⁵, Jarkko Harju⁴, Aldo Rustichini⁶, Andrea Ganna^5,7,8

¹VATT Institute for Economic Research, Helsinki, Finland. ²IFAU and Uppsala Center for Labor Studies, Uppsala, Sweden. ³IZA, Bonn, Germany, 53113, and Rockwool Foundation, Berlin, Germany. ⁴Economics department at Tampere University, and FIT, Tampere, Finland. ⁵Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland. ⁶Economics department at University of Minnesota, Minneapolis, USA. ⁷Broad Institute of MIT and Harvard, Cambridge, USA. ⁸Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, USA

T38. The Role of Neighborhood Social Processes and Deprivation in Moderating Genetic and Environmental Influences on Parenting During Middle Childhood

Stuart Rand¹, Alexandra Burt², Kelly Clump², Elizabeth Shewark¹

¹University of Notre Dame, Notre Dame, USA. ²Michigan State University, East Lansing, USA

**Early Career Presentation

T39. Gene × Environment Interactions in the Development of Social Competence: The Role of Parental Self-Regulation and Sociability

Zhaoying Chen¹, Amani Khan¹, Leslie Leve², Jenae Neiderhiser³, Daniel Shaw⁴, Misaki Natsuaki⁵, Jody Ganiban¹

¹George Washington University, Washington, DC, USA. ²University of Oregon, Eugene, Oregon, USA. ³The Pennsylvania State University, University Park, Pennsylvania, USA. ⁴University of Pittsburgh, Pittsburgh, Pennsylvania, USA. ⁵University of California, Riverside, Riverside, California, USA

**Early Career Presentation

T40. Does Heritability of Birth Mother Positive Affectivity Buffer the Effects of Household Chaos on Child Socioemotional Outcomes?

Madison Newell¹, Leslie D. Leve², Misaki Natusuaki³, Jenae M. Neiderhiser⁴, Daniel Shaw⁵

¹The George Washington University, Washington, USA. ²University of Oregon, Eugene, USA. ³University of California - Riverside, Riverside, USA. ⁴The Pennsylvania State University, University Park, USA. ⁵University of Pittsburgh, Pittsburgh, USA

**Early Career Presentation

T41. The Intergenerational Transmission of Loneliness in Adopted Children

Natalie Byrd¹, Chia-li Yu¹, Jody Ganiban², Leslie Leve³, Daniel Shaw⁴, Misaki Natsuaki⁵, Jenae Neiderhiser¹

¹The Pennsylvania State University, State College, USA. ²George Washington University, Washington, USA. ³University of Oregon, Eugene, USA. ⁴University of Pittsburgh, Pittsburgh, USA. ⁵University of California, Riverside, USA

**Early Career Presentation

T42. Exploring attrition bias in TEDS: predictors, consequences, and corrections

Giacomo Bignardi¹, Thalia Eley¹, Celestine Lockhart¹, Christopher Rayner¹, Kate Tilling^2,3, Tom A. McAdams¹

¹Social, Genetic & Developmental Psychiatry Centre, King's College London, London, United Kingdom. ²MRC Integrative Epidemiology Unit, University of Bristol,, Bristol, United Kingdom. ³Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

T43. Using a Normal Finite Mixture Distribution Twin Model When Zygosity Is Unknown: Bias and Robustness

Madelief I. Kuijper¹, Abe D. Hofman^2,3, Elsje van Bergen^1,4, Bruno Sauce¹

¹Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Psychological Methods, Universiteit van Amsterdam, Amsterdam, Netherlands. ³Prowise Learn, Amsterdam, Netherlands. ⁴PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway

**Early Career Presentation

T44. Ranking versus Homophily in Assortative Mating: A Structural Model with Stable Matching and Implications for Social Stratification

Luca Donghi¹, Aldo Rustichini¹, Riccardo Vergnano²

¹University of Minnesota, Minneapolis, USA. ²Università degli Studi di Genova, Genova, Italy

**Early Career Presentation

**Public Science Presentation

T45. Age at Onset and Liability to Disorder: Correcting for Censoring

Michael Neale

Virginia Commonwealth University, Richmond, USA

T46. Genetic Clustering to Identify Etiological Subtypes: A Novel Approach to Characterizing the Heterogeneity within Psychopathology

Qingyue Yuan, Tianyuan Lu, James Li

University of Wisconsin - Madison, Madison, USA

**Early Career Presentation

**Public Science Presentation

T47. Integrating PoPS-Based Gene Prioritization and Predicted Gene Expression for Systematic Drug Repurposing

Nathaniel Bell¹, Emil Uffelmann¹, Eva van Walree², Christiaan de Leeuw¹, Danielle Posthuma¹

¹Vrije Universiteit Amsterdam, Complex Trait Genetics Lab, Amsterdam, Netherlands. ²Amsterdam University Medical Center, Amsterdam, Netherlands

**Early Career Presentation

T48. Across-species meta-analysis of GWAS results for DZ twinning

Dorret I. Boomsma¹, Marijn Schipper¹, International Twinning Genetics Consortium², Christin Schmidtmann³, Brian W. Kirkpatrick⁴, Nikki Hubers^5,6

¹Complex Trait Genetics, VU, Amsterdam, Netherlands. ²www.twinningconsortium.org/community/, Amsterdam, Netherlands. ³IT-Solutions for Animal Production (vit), Verden, Germany. ⁴Department of Animal and Dairy Sciences, University of Wisconsin, Madison, USA. ⁵National Centre for Register-based Research, Aarhus Uni, Aarhus, Denmark. ⁶The SMARTBiomed Pioneer Centre, Aarhus University, Aarhus, Denmark

T49. Cross-cohort GWAS meta-analysis of scale-free EEG dynamics (DFA and fEI) nominates genome-wide and suggestive loci despite limited power

Yuchen Ning, Dirk Smith

Amsterdam University Medical Centre, Amsterdam, Netherlands

T50. A novel method for linking brain activity to neuropsychiatric disorders: combining machine learning and polygenic scoring in the ENIGMA-EEG cohorts

Lotte Troost¹, Yuchen Ning¹, Dirk Smit¹, René Pool², Lannie Ligthart², Conor Colan²

¹AUMC, Amsterdam, Netherlands. ²VU Amsterdam, Amsterdam, Netherlands

**Early Career Presentation

T51. APOE ε4 Modulates the Cognitive Impact of Genetically Predicted Chronic Inflammation: Evidence from Two Swedish Cohorts

Emilija Romic¹, Ida Karlsson², Nina Karalija¹, Karolina Kauppi^1,2

¹Umea University, Umea, Sweden. ²Karolinska Institutet, Stockholm, Sweden

T52. From Genetics to Gen-Ethics: Exploring Genetics and GWAS Methodologies through an Ethical Lens in Undergraduate Education

Wonuola Akingbuwa^1,2, Margot van de Weijer³

¹Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands. ²Amsterdam Public Health Research Institute, Amsterdam, Netherlands. ³Genetic Epidemiology, Department of Psychiatry, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands

**Community, Accessibility, & Growth Presentation

**Public Science Presentation

T53. Exploring Public Understandings of Genetics and Genetics Research in the Midwestern United States: A Qualitative Analysis

Kathryn Malerbi, Robbee Wedow

Purdue University, West Lafayette, USA

**Early Career Presentation

**Public Science Presentation

T54. Studying an age-of-sale policy reform in the Netherlands: A genetically informed design

Emily A. Poort^1,2,3, Saar Mollen^3,4, Jorien L. Treur¹, Karin J.H. Verweij¹, Yayouk E. Willems⁵, Margot P. van de Weijer^1,2,3

¹Department of Psychiatry, Amsterdam UMC, Amsterdam, Netherlands. ²Amsterdam Public Health Institute, Amsterdam UMC, Amsterdam, Netherlands. ³Centre for Urban Mental Health, University of Amsterdam, Amsterdam, Netherlands. ⁴Department of Communication Science, University of Amsterdam, Amsterdam, Netherlands. ⁵Max Planck Research Group Biosocial – Biology, Social Disparities, and Development; Max Planck Institute for Human Development, Berlin, Germany

**Early Career Presentation

T55. Pharmacogenetics test utility depends on ancestry groups and antidepressant medication

Baptiste Couvy-Duchesne¹, Penelope Lind¹, Jodie Painter¹, Greg Pratt², Sarah Medland¹

¹QIMR Berghofer, Brisbane, Australia. ²CQ University, Brisbane, Australia

**Community, Accessibility, & Growth Presentation

**Public Science Presentation